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04/02/2001 I:)u Pont Page 5 of 12 Material Safety Data Sheet - 12395S - CHROMAPREMIER ****** SECTION 3 - Hazards Information ****** Potential Health Effects: Inhalation: May cause nose and throat irritation. May cause nervous system depression characterized by the following progressive steps: headache, dizziness, nausea, staggering gait, confusion, unconsciousness. Reports have associated repeated and prolonged overexposure to solvents with permanent brain and nervous system damage. If this product contains or is mixed with an isocyanate activator/hardener, the following health effects may apply: Exposure to isocyanates may cause respiratory sensitization. This effect may be permanent. Symptoms include an asthma-like reaction with shortness of breath, wheezing, cough or permanent lung sensitization. This effect may be delayed for several hours after exposure. Repeated overexposure to isocyanates may cause a decrease in lung function, which may be permanent. Individuals with lung or breathing problems or prior reactions to isocyanates must not be exposed to vapors or spray mist of this product. Ingestion: May result in gastrointestinal distress. Skin or eye contact: May cause irritation or burning of the eyes. Repeated or prolonged liquid contact may cause skin irritation with discomfort and dermatitis. Other Potential Health Effects in addition to those listed above: ALIPHATIC POLYISOCYANATE RESIN Overexposure may cause asthma-like reactions with shortness of breath, wheezing, cough, which may be permanent; or permanent lung sensitization. This effect may be delayed for several hours after exposure. Repeated exposure may cause allergic skin rash, itching, swelling. May cause eye irritation with discomfort, tearing, or blurred vision. Repeated overexposure to isocyanates may cause lung injury, including a decrease in lung function, which may be permanent. Individuals with preexisting lung disease, asthma or breathing difficulties may have increased susceptibility to the toxicity of excessive exposures. AROMATIC HYDROCARBON-B Laboratory studies with rats have shown that petroleum distillates can cause kidney damage and kidney or liver tumors. These effects were not seen in similar studies with guinea pigs, dogs, or monkeys. Several studies evaluating petroleum workers have not shown a significant increase of kidney damage or an increase in kidney or liver tumors. BIS(1,2,2,6,6-PENTAMETHYL-4-PIPERDINYL) SEBACATE Repeated exposure may cause allergic skin rash, itching, swelling. BUTYL ACETATE May cause abnormal liver function. Tests for embryotoxic activity in animals has been inconclusive. Has been toxic to the fetus in laboratory animals at doses that are toxic to the mother.