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Section 11. Toxicological information <br /> Information on toxicological effects <br /> Acute toxicity <br /> Productringredient name Result Species I Dose Exposure <br /> Calcium Carbonate LD50 Oral Rat 6450 mg/kg <br /> I rritati ordCorrosion <br /> ProducVingredient name Result Species Score Exposure Observation <br /> Calcium Carbonate Eyes-Severe irritant Rabbit 24 hours 750 - <br /> Micrograms <br /> Skin-Moderate irritant Rabbit 24 hours 500 - <br /> Milligmms <br /> Titanium Dioxide Skin-Mild irritant Human 72 hours 300 - <br /> Micrograms <br /> Intermittent <br /> Tetram ethyl Decynediol Eyes-Severe irritant Rabbit O.1 Mililiters <br /> Skin-Mild irritant Rabbit 0.5 Grams <br /> Sensitization <br /> Not available. <br /> Muraaenicity <br /> Not available. <br /> Carcinogenicity <br /> Not available. <br /> Classification <br /> Product ingredient name OSHA IARC I NTP <br /> Crystalline Silica, respirable 1 Known to be a human carcinogen. <br /> powder <br /> Titanium Dioxide 2R <br /> Reproductive toxicitv <br /> Not available. <br /> Teratogenicity <br /> Not available. <br /> Specific target organ toxicity Isinale exposure) <br /> Not available. <br /> Specific tarter organ toxicity Irepeated exposure) <br /> Name Category Route of Target organs <br /> exposure <br /> Crystalline Silica, respirable powder Category 1Inhalation Not determined <br /> Mip Category 1 Inhalation lungs <br /> Aspiration hazard <br /> Not available. <br /> Dare oflssueNare of�evlslm :992017 Daeedgevbaslssue :41f 17 wish :e W12 <br />