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Anheuser-Busch/Arch Road Site Safety Plan February 11, 1992 6.1 $,pill and Disposal Procedures Contain spills with an absorbent material (sand, sawdust, dirt, clay) . Report spills to client and follow their recommended procedures. If spills occur in transit, report them to the appropriate authorities. 7.0 CHEMICALS OF CONCERN 7.1 Health Effects Potential health effects from a chemical exposure are dependant on several exposure factors such as: toxicity of substances, duration of exposure, concentration during exposure and the overall health of the person exposed. The chemicals commonly at this site are: Gasoline, Benzene, Toluene, Ethylbenzene, and Xylene. The following is a health analysis of these chemicals. Additional information on these chemicals can be found in the Material Safety Data Sheet located in Appendix I. Gasoline constituents can be divided into five major groups: alkanes, alkenes, cycloalkanes, aromatics and additives. The aromatics are the constituents generally regarded to be of greatest toxic concern. The major aromatics in gasoline are benzene, toluene, ethyl benzene and xylene. Of these, benzene is considered to be the most toxic. One characteristic effect of gasoline and its aromatic constituents is their ability to irritate the skin when repeated or prolonged exposure occurs. Benzene Benzene can enter the body through inhalation, ingestion and skin contact. Studies have noted that chronic exposure to benzene vapor can produce neurotoxic and hematopoietic (blood system) effects. Other effects can include headache, dizziness, nausea, convulsions, coma and possible death if exposure is not reversed. One significant effect from chronic benzene exposure is bone marrow toxicity. There is also an association between chronic exposures to benzene and the development of certain types of leukemia. 15