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` 66.29
<br /> AnchraCe,ne
<br /> AArhracene.% asserts phoc0tz%1a and pao=oailerglc action on the
<br /> Soxic jCi27. C 1S CarCiIIogenXC-Ljjy LtZacLlVe (12). Various
<br /> lovasc toxic tuuaer tstudies have
<br /> h produced nega� 15
<br /> ve responses _(23 ) .oral dose LA the raz is- 20 g/kg� (47) . The
<br /> __ _
<br /> The toxxc"y of selected fuel oLL addicives> is outliacd,belov.
<br /> � � ' � , Yt�,��, ,tisyye @ ��� .,t K� � i : a �.UL�� • 1� 4"} d r� r��bo. �� '
<br /> t" gsa,lr of f��tS!' i the CN$
<br /> r�chrdnic 'fast-, known,,'aa rams .> " Iataxxcatfort ~occurs mostly "in ''the L
<br /> gaxusm vhichy 'is _ssmilarr ;tor 'Par'kinsonfs�,
<br /> Usually 'inaaganism�'oecurs , aftar 'L-2 years ' expos`ure 'tor ieaasganese ,oxides
<br /> although L`c `,r`may `develop', after only a few ,mdnchs.` ,'Initial symptoms
<br /> Includa 'headache, _azr-henLa" (loss a f s tree th and er:er
<br /> sleep and persoiiali 3 gy) . restless
<br /> horse v change. This , Ls followed by an witntertaediare
<br /> P LCa ,.,vzsual hal Luciriatians._' ,daublc ,vision,
<br /> �r! uneon=rollabl�e �,umulse''s � �aLred hearing
<br /> _ mettui '
<br /> ,_�,,�,..,� ,� ,_ � i -,canfusian ander euphoria, ;In advaiicad
<br /> stages. theFApacmenc experiences*e. t-;�f ( y M
<br /> a _ 'Ccessive sal�iracion, ,muscle weakness.
<br /> muscle 'rigidi'cv. _ tremor, of the ugpex; ex=remL=Les `and4haad, and-Lmpalred
<br /> pelt~ FrLaam ngariLsm wsth�lrie""uroeogic�`symptams., che�cnurse is frequeaI
<br /> Progressive;r ajlrhough some cases are "stacrtonary arid' ' ethers recover
<br /> (2.46), A
<br /> t �5 k 0 �{ � i • fy ! A+ r.� r �L i l `7 wlwl"�iA �J � 5 *� F
<br /> Lnhalition of
<br /> high '`concencr=rLonz ,of'manganese ,oxide causes mesal
<br /> fume fever - c,aw 24-48 y t,� y
<br /> achxn
<br /> : hazer Lllaess ch chills.1bjr5tw ch11ls. Fever.
<br /> .f �w gFsauscles4 arywmauch'",and,lchroac. and_h"ead,Ckje (46) �dt
<br /> ~6x F 4 t'� Y � t f �diL • tl r 1 Y •
<br /> �d enrSl��
<br /> 0,C 71 "1 11 A, M
<br /> Magnesium oxide Eames are trrzta=Lng to the eves and nose. It.
<br /> also causes metal fume fever vhlch is a 24-4-8 hour znfluenza-type
<br /> Illness (46)
<br /> ALuminum oxide is a nuisance dust. which has Li=tie adverse effect-
<br /> On Me Lungs ac low exposure levels.
<br /> Excessive concentracLons may
<br /> cause deposits in the eves . ears and nasal passages_ or-may cause mild
<br /> tn)ury to rile skLn`arid-mucous-memoranes (46)
<br /> In general. peroxides are strong axidLzLng
<br /> Lrr,ta=zon, hums or eye damage (200) agents capable of skin
<br /> 6/87
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