Laserfiche WebLink
Benzene <br /> mSDS-1121 <br /> Page 3 <br /> SECTION IV. LONG-TERM ORGANISM THREAT POTENTIAL <br /> Carcinogenicity <br /> IARC: Limited evidence of carcinogenic effects in animals . Sufficient <br /> evidence of carcinogenic effects in humans. <br /> NTP/NCI: NTP/NCI has reported carcinogenic effects . <br /> CAG has reported carcinogenic effects. <br /> R' CS: Carcinogenic by RTECS criteria based on cases of leukemia in <br /> umans and rats. Carcinogenic by RTECS criteria in mice. <br /> Muta enicity <br /> AR Not mutagenic in bacteria, yeast, insects , or mouse lymphoma <br /> ceTTs. Chromosomal anomalies in humans, rats, and mice were observed. <br /> RTECS: Positive <br /> were obsery d mutagenic <br /> nDNA responses <br /> e in <br /> and breaks inhumans <br /> and <br /> r abs <br /> were observed. <br /> Terato enicity <br /> ARC' lail abnormalities, cleft palate, and absence of the lower jaw <br /> were defects observed in mice. Brain and skeletal defects in rats were <br /> observed. Other studies did not show teratogenic effects . <br /> RTECS: Abnormalities of the musculoskeletal system and other effects <br /> onFe newborn were observed in rats and mice. <br /> Reproductive Effects <br /> AR teration of estrus cycles in rats was observed. Increased <br /> testicular weight and degeneration of the seminiferous tubules in rats , <br /> guinea pigs , and rabbits were observed. Fetotoxicity in rats and mice <br /> were observed. <br /> RTECS: Fetotoxicity, post-implantation mortality, and extra embryonic <br /> structures in rats and mice were observed. Pre-implantation mortality, <br /> fetal death, and other fetal effects in mice were observed. <br /> SECTION V. CHRONIC TOXICITY <br /> Appetite oss , weight loss , fatigue, muscle weakness , headaches, <br /> dizziness, nervousness , irritability, anemia, irreversible blood changes, <br /> and damage to the heart and liver. <br /> SECTION VI. PHYSICAL DATA <br /> Molecular weight: 78.12 <br /> Boi in Point at 760 mm Hg): 80`C (176oF) <br /> Me tinPoint at 0 mm H 5 .50C (42 F) <br /> Vapor Pressure mm H at 20 C (68'F)] : <br /> 74.6 <br /> Vapor Density Air= : <br /> Specific Gravity water=l): 0.879 <br /> Percent Volatile By o ume: 100 <br /> Evaporation Rate uty acetate =1): 1 <br /> So u ity in water: Soluble <br /> Solvent o u i ity: Miscible with alcohol , chloroform, ether , carbon <br /> oisu i e, car on----5---Tetrachloride, glacial acetic acid, acetone, oils . <br /> Appearance and Odor: Clear, colorless , flammable liquid with an odor <br /> threshold o ppm• <br /> Fnyi,-nlnnJr ENVIRO10ciC BATA <br />