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r.. 1 <br /> g „enzene <br /> -4SOS-1121 <br /> Page 3 <br /> SECTION IV. LOVG—TERM ORGANISM THREAT POTENTIAL <br /> Carcina enicit <br /> --FARr. Limited evidence of carcinogenic effects in animals. Sufficient <br /> " e ry aence of carcinogenic effects in humans. <br /> NTP/NCI• NTP/NCI has reported carcinogenic effects. <br /> SAG has reported carcinogenic effects. <br /> MCS: Carcinogenic by RTECS criteria based on cases of leukemia in <br /> u�ans and rats. Carcinogenic by RTECS criteria in mice. <br /> Mutagenicity <br /> R Nat mutagenic in bacteria, yeast, insects, or crouse lymphoma <br /> ce s. Chromosomal anomalies in humans, rats, and mice were observed. <br /> RTECS: Positive mutagenic responses in bacteria, mice, rats, and <br /> �a lts were observed. DNA damage and chromosomal breaks in humans <br /> were observed. <br /> Terata enicit <br /> C: az abnormalities, cleft palate, and absence of the lower jaw <br /> were defects observed in mice. Brain and skeletal defects in rats were <br /> observed. Other studies did not show teratogenic effects. <br /> RTECS: Abnormalities of the musculoskeletal system and other effects <br /> on the newborn were observed in rats and mice. <br /> Reproductive Effects <br /> EM <br /> AM IARL;: teration of estrus cycles in rats was observed. Increased <br /> testicular weight and degeneration of the seminiferous tubules in rats, <br /> guinea pigs, and rabbits were observed. Fetotoxicity in rats and mice <br /> were observed. <br /> RTECS: Fetotoxicity, post—implantation mortality, and extra embryonic <br /> structures in'.rats and mice were observed. Pre—implantation mortality, <br /> fetal death, and other fetal effects in mice were observed. <br /> SECTION V. CHRONIC TOXICITY <br /> Appetite Toss, weight loss, fatigue, muscle weakness, headaches, <br /> dizziness, nervousness, irritability, anemia, irreversible blood changes, <br /> and damage to the heart and liver. <br /> SECTION VI. PHYSICAL DATA <br /> - <br /> Molecular .rel vh t: 78.12 <br /> Bar + rna Parnt (at 750 rm b): ou <br /> feitin5^ a) ' (1=Z',-) <br /> Vapor Pressure {mmiQ1 at _0'C (63'=i1 74.8 <br /> 'lacor Density <br /> Specific GTavlty F5drer=1): O.g79 <br /> on Percent VolaFe 8y `/o+ume: 1G0 <br /> Evagorat7cn Rateb (duty+ acatate }: <br /> So+ur + rty in Water: .aloe+a <br /> VL So vent 3o+uoi rty: 11isciblL' ;With a1c0hoi , chlor•ofor:i, ether, carbon <br /> cis rrae, carbon tetrachloride, claci•il acetic acid, acetone, oils. <br /> Aire not and Odor: Clear, colorless, fla+rmable liquid with an odor <br /> Cnre5n0+ Or ppm. <br /> Copyright 1984 by Envirologic Data, Inc. <br /> 4.57 <br />