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Message • • Page 1 of 2 <br /> Vicki McCartney [EH] <br /> From: George Forsythe[gforsythe@secor.com] <br /> Sent: Friday, April 15, 2005 2:28 PM <br /> To: Vicki McCartney [EH] <br /> Cc: Darin Rouse; sfurgal@secor.com <br /> Subject: FW: Silica Gel Cleanup <br /> Hi Vicki; <br /> I'm forwarding Lancaster Laboratory's response regarding the request to"report the toxicity of polar compounds". <br /> They appear to be somewhat perplexed by the request as am 1. Could you elaborate some on exactly what you'd like to see? <br /> Thanks; <br /> George <br /> -----Original Message----- <br /> From: tcunningham@lancasterlabs.com [mailto:tcunningham@lancasterlabs.com] <br /> Sent: Friday, April 15, 2005 10:07 AM <br /> To: gforsythe@secor.com <br /> Subject: RE: Silica Gel Cleanup <br /> Hi George, <br /> I received the following response from Bob Brown regarding Vicky's request: <br /> We have no way of knowing what(polar) compounds are removed from a given sample when treated with silica <br /> gel, unless we get into some additional and elaborate fractionation/ion exchange prep procedures followed by <br /> GUMS analysis. Therefore, under current methodologies that we follow, we cannot comment on these <br /> compounds. <br /> Bob will give you a call later today to discuss chromatogram interpretation and other subjects that you might be <br /> interested. Please let me know if I can get you anything else. <br /> Thanks, <br /> Teresa <br /> -----Original Message----- <br /> From: George Forsythe [mailto:gforsythe@secor.com] <br /> Sent: Thursday, April 14, 2005 11:18 AM <br /> To: Teresa L. Cunningham <br /> Subject: FW: Silica Gel Cleanup <br /> Hi Teresa; <br /> This is the email that I received from a regulatory person. Can you shed any light on what she is requesting <br /> when she asks that we "report the toxicity of polar compounds" I understand the idea of polar molecules,but <br /> I cannot put it in to the context of her request. <br /> Thanks; <br /> George Forsythe <br /> -----Original Message----- <br /> From: Vicki McCartney [EH] [mailto:vmccartney@sjcehd.com] <br /> 4/15/2005 <br />