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a 316 :3enzcrc 8/90 . e
<br /> Section 6. Hel`ltth°Hazard Dat9 '
<br /> Carcinogenicity a ist nzcxic as, respective y,a sir �n uman carcinogen, a cancer hazaRiFd: as 'bn
<br /> si.fricicnt human and animal evidence,a human carcinogen(Group 1)
<br /> Summar} of Risks Prolonged skit contact or excessive ulhalation of benzene vapor may cause headache,weakness appetite loss,and fattgu'c
<br /> The most important health hazards are cancer(leukeriva)and bone marrow damage with injury to blood-forrnuig ussuC Gam chronic low-level
<br /> exposure Higher level exposures may imtatc the respiratory tract and cause central nervous system(CNS)depression
<br /> Medical Conditions Aggravated by Long-Term Exposure Exposure may u orsen ailments of the heart,lungs,liver,kidneys,blood,and CNS
<br /> Target Or ans.Blood,central ncr'vous system.bone marrow,eyes,upper respiratory tract, and skin '
<br /> Primary Entry Routes:lithalaticai,skin contact.
<br /> Acute Effects. Symptoms of acute overexposure mclude imtation of the eyes,nose,and respiratory tract,breathlessness,euphoria,nausea,
<br /> drou smess,headache,dimness,and intoxication Severe exposure may lead to convulsions and unconsciousness Skin contact may cause a
<br /> dr)ing rash(dermatitis) - , 0 J
<br /> Chronic Effects Long-term chrorue exposure may result to many blood disorders ranging from aplastic anemia(an iriabtlity to form blood cells) 0
<br /> to leukerrua.
<br /> FIR ST AID
<br /> Eyes Gently lift the eyelids and flush immediately and continuously with flooding'amounts of water until transported to an emergency medical -
<br /> facility Consult a physician immediately I
<br /> Skin Quickly remove contanimated clothing Immediately raise with flooding amounts of water for at least 15 mai For reddened or blistered '
<br /> sl.in,consult a physician.Wash affected area with soap and water ,
<br /> Inhalation Remove exposed person to fresh air Emergency personnel should protect agamst inhalation exposure Provide CPR to support
<br /> breathing or circulation as necessary Keep awake and transport to a medical facib - A T
<br /> Ingestion Never&ive anything by mouth to an unconscious or convulsing person.If ingested,do nor induce vomutng since aspiration may be
<br /> fatal Call a physician immediately < '
<br /> After first aid,get appropriate in-plant,paramedic,or dcommunity medical suppor-L
<br /> Phystclan's Note Evaluate chronic exposure with a CBC,peripheral smear,and reticulocyte count for signs of myelotoxicity Follow up any ,
<br /> eary indicators of leukemia with a bone marrow biopsy Urinary phenol conjugates maybe used for biological morutormi;of recent exposure
<br /> Acute management is prumnly supportive for CNS depression '
<br /> Section 7, Spill,Leak, and Visposal Procedures
<br /> SpdVLeak-Design and practice a benzene spill control and countermeasure plan(SCCP) Notify safety personnel,evacuate all unnecessary
<br /> personnel,eliminate all heat and ignition sources,and provide adequate ventilation Cleanup personnel should protect against vapor inhalation,eye ='
<br /> contact, and skin absorption Absorb as much benzene as possible with an alert,noncombustible material For large spills,dike far ahead of spill
<br /> and contain liquid.Use nonsparking tools to place waste liquid or absorbent mid-closable eontamers for disposal Keep waste out of confined
<br /> spaces such as sewers,watersheds, and waterways because of explosion danger Follow applicable OSHA regulations(29 CFR 1910 120)
<br /> Disposal Contact your supplier or a licensed contractor for detailed recommendations Follow applicable Federal,state,and local regulations
<br /> EPA Designations - s
<br /> Listed as a RCRA Hazardous Waste(40 CFR 26133),Hazardous Waste No U019
<br /> Listed as a CERCLA Hazardous Substance*(40 CFR 302 4) Reportable Quantity(RQ) 1000 lb(454 kg)[*per Clean Water Act,Sec 307(a)
<br /> 311 (b)(4), 112,and per RCRA.Sec 3001] 1 . 1 -
<br /> SARA Extremely Hazardous Substance(40 CFR 355) Not listed
<br /> Luted as SARA Toxic Chemical(40 CFR 372 65)
<br /> OSHA Designations
<br /> Luted as an Air Contaminant(29 CFR 1910 1000 Tables Z-L--A and Z-2)
<br /> Section 8. Special�-crtectian Date; -
<br /> -Goggles Wear-protective eyeglasses or cherrucal safety goggles,per OSHA eye-and face-protection regulations(29 CFR-1910 133) p
<br /> Respirator.Seek professional advice prior t6--respirator selecti6ri and d e-Follow OSHA respirator rCgulations(29 CFR-1910 134)and,if neves- °_T—
<br /> sary,wear a NIOSH-approved respirator For emergency or nonroutine operations(cleaning spills,reactor vessels,or storage tanks),wear an
<br /> SOBA Warnung l Air-purifying respirators do not protect workers in oxygen-deficient atmospheres
<br /> Other Wear impervious gloves,boots,aprons,and gauntlets to prevent skin contact.
<br /> Ventilation Provide general and local explosion-proof ventilation systems to mauitain airborne concentrations at]cast below the OSHA PELs
<br /> (Sec 2) Local exhaust ventilation is preferred since it prevents contarnmant dispersion into the work area by controlling it at its source
<br /> Safety Stations.Make available in the work area emergency eyewash stauons,safetylquick-drench showers, and waslung facilities ' '
<br /> Contaminated Equipment.Never wear contact leases in the work arm soft lenses may absorb, and all lenses concentrate,untants Remove this
<br /> material from your shots and equipment.Launder contammased clothing before wearing-
<br /> Comments:Never eat;drink„or mea
<br /> smoke in work s Prati
<br /> cceoo
<br /> gd personal hygiene after usmg this ihatenal,Tespecially before eating,dnnlang,
<br /> smokin ,us the toilet,or aE2lXm&cosmetics '
<br /> Section 9. SPO"al-Precaudans and,Comments n v ri x
<br /> Storage Requirements:Store m tightly closed containers m a cool,dry,well-ventilated area away from all heat and igrution sources and
<br /> incompatible inatenals Cautcont Benzene vapor may form explosive rruziures tit air To prevent static sparks,electncaily ground and bond,all
<br /> containers and equipment used in sluppmg,receiving,or transferring operations rn production and storage areas When opening or closing '
<br /> benzene containers,use nonsparking tools Keep fire extinguishers readily available `
<br /> Frigincering Controls Because OSHA specifcalIy regulates benzene(29 CFR 1910 1028) educate workers about its potential hazards arid
<br /> Gangers Mmmuze all possible exposures to carcuiogem If possible,substitute less toxic solvents for benzene,use tlus material with extreme
<br /> caution and only if absolutely ess--nual.Avoid vapor inhalation and skin and eye contact. Use only with adequate ventilation and appropnate
<br /> personal protective gear Institute a respiratory protection program that includes regular tratrung maintenance,inspection,and evaluation- '
<br /> Designate regulated areas of benzene use(see legend in the box below)and label benzene containers with'DANGER CONTAINS BENZENE,
<br /> CANCER HAZARD'
<br /> Other Precautions Provide preplacement and penodic medical examinations with emphasis on a history of blood disease or previous exposure
<br /> Transportation Data(49 CFR 172 I01, 102)
<br /> DOT Shipping Name Benz=(benzo!) IMO Shipping Name Benzene DANGER
<br /> DOT Hazard Class- Flammable liquid IMO Hazard Class. 3 2 BENZENE
<br /> JD No UN1114 ID leo UN1114 CANCER HAZARD
<br /> DOT Label Flammable liquid IMO Label Flammable liquid FLAMMABLE-NO SMOKNG ( ;
<br /> DOT Packaging Exceptions 173 118 IMDG PackagJng Group II ALMIORIZED PERSONNEL ONLY
<br /> f DOT Packaging Requirements 173 119 RESPIRATOR REQUR D
<br /> t AfSDS Collection References 1 2 12 26 73,84-94 100 101 103 109 124 126 127 132 134 136 138 139 143
<br /> Prepared by Ml Aticsai,BS Industrial Hygiene Review D7 Wdson,CEH Medical Review MJ Up51,MD MPH Edited by IR Stuart MS 4 ,I
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