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action 6 Health Hazard Data <br /> Medical Conditions Aggravated by Long-Term posure Alcoholism and CNS,kidney,skin,or lnv ease Target Organs CNS,liver, <br /> )adney skin Primary Entry Routes Inhalation,skin contact/absorpuon Acutt Effects.Vapor inhalation causes respiratory tract iritauon,fatigue, " <br /> �%eaknrss confusion,dizziness, headache,dilated pupils watering eyes nervousness,insomnia.,pamsthesis,and vertigo progressing to narcotic coma <br /> Death may result from cardiac arrest due to ventricular fibrillation with catecholamines loss Liquid splashed in the eye causes conjunctival irritation <br /> transient corneal damage and possible burns Prolonged sLin contact leads to drying and fissured dcrmatius Ingestion causes GI tract irritation and ' <br /> s)mptoms associated with inhalation Chronic Effects Symptoms include mucous membrane imtauon,headache,vertigo,nausea,appetite loss and <br /> .ilcohol intolerance Repeated heavy exposure may result in encephalopathies(cerebellar ataxia and cognitive dysfunction) liver enlargement, and <br /> kidney dystrophy(wasting away) Symptoms usually appear at workdays end;worsen at weeks end and decrease or disappear over the weekend , <br /> FI RST AID Eyes.Do not allow victim to rub or keep eyes lightly shut_Gently lift eyelids and flush immediately and continuously with flooding <br /> imounts of water until transported to an emergency medical facility Consult an ophthalmologist immediately Skin Quickly remove contaminated <br /> clothing Rinse with flooding amounts of water for at least 15 min Wash exposed area with soap and water Inhalation Remove exposed personlo <br /> fresh air and support breathing as needed Ingestion Never give anything by mouth to an uncoriscious or convulsing person Contact a poison control e' <br /> center and unless otherwise advised,have that conscious and alert person drink I to 2 glasses of water to dilute Do not induce vomiting because of <br /> danger of aspiration into the lungs Gastric lavage may be indicated if large amounts are swallowed,potential toxicity needs to be weighed against <br /> aspiration risk when deciding for or against gastric lavage Dote to Physicians Monitor cardiac function If indicated,use epinephrine and other <br /> catecholammes carefully,because of the possibility of a lowered myocardial threshold to the arrhythmogenic effects of such substances Obtain CBC ' <br /> electrolytes,and unnalysis Monitor arterial blood gases If toluene has>0 02%(200 ppm)benzene,evaluate for potential benzene toxicity BEI <br /> hippunc acid in urine,sample at shift end(2.5 g/g creatinine),Toluene in venous blood,trample at shift end(1 0 mg/L) <br /> Section 7, Spill, Leak,and Disposal Procedures <br /> Spill/Leak Notify safety personnel,isolate and ventilate area,deny entry,and stay upwind Cleanup personnel protect against inhalation and skin/eye , <br /> contact_Use water spray to cool and disperse vapors but it may not prevent igruuon in closed spaces Ceilosolve,hycar absorbent materials and <br /> fluorocarbon water can also be used for vapor suppress ion/con tain men L Take up small spill with earth,sand,vermiculite,or other absorbent, <br /> noncombustible material Dike far ahead of large spills for Iater reclamation or disposal For water spills,(10 ppm or greater)apply activated carbon at <br /> IOX the spilled amount and remove trapped material with suction hoses or use mechanical dredges/lifts to remove immobilized masses of pollutants ' <br /> and precipitates Toluene can undergo fluidized bed incineration at 842 to 1796'F(450 to 980'C),rotary kiln incineration at 1508 to 2912'F(820 to <br /> 1600 C),or liquid injection incineration at 1202 to 2912'F(650 to 1600'C) Follow applicable OSHA regulations(29 CFR 1910 120) Ecotoxicity <br /> V.ilues Blue gill,LCso= 17 mg/L124 hr;shrimp(Crangonfracis coron), L.Cso=43 ppnv96 hr,fathead minnow(Pimephales prormlas),LCSo=36 2 <br /> mg/W6 hr Environmental Degradation If released to land,toluene evaporates and undergoes microbial degradation In water toluene volatilizes ' <br /> and biodegrades with a half-life of days to several weeks In air,toluene degrades by reaction with photocherracally produced hydroxyl radicals <br /> Disposal Treat contaminated water by gravity separation of solids,followed by skimming of surface Pass through dual media filtration and carbon <br /> .ibsoiption units(carbon ratio 1 kg to 10 kg soluble material) Return waste water from backwash to gravity separator Contact your supplier or a <br /> licensed contractor for detailed recommendations Follow applicable Federal,state,and local regulations ' <br /> EPA Designations -` OSHA Designations <br /> Listed as a RCRA Hazardous Waste(40 CFR 26133) No U220 Listed as an Air Contaminant(29 CFR 1910 1000,Table Z-1-A) <br /> SARA Extremely Hazardous Substance(40 CFR 355) TPQ Not listed <br /> Listed as a CERCLA Hazardous Substance's(40 CFR 302 4) Final Reportable Quantity(RQ), 1000 lb(454 kg) <br /> [*per RCRA,Sec 3001,CWA,Sec 311 (b)(4),CWA Sec 307(a)] <br /> Listed as a SARA Toxic Chemical(40 CFR 372 65) Not listed <br /> Section S. Special Protection Data <br /> Goggles Wear protective eyeglasses with shatter-resistant glass and side shields of cherrucal safety goggles,per OSHA eye-and face-protection - - <br /> egulations(29 CFR 1910 133) Because contact lens use in industry is controversial,establish your own policy Respirator Seek professional <br />—!.-cd%ice prior to respirator selection and use Follow OSHA respirator regulations(29 CFR 1910 134)and,if necessary,wear a MSHA/NIOSH <br /> Ippro,ed respirator For<100 ppm,use any chemical cartridge respLm-Lor with appropriate orgaruc vapor cartridges any supphed-au respirator <br /> € t.S AR),or SCBA For<200 ppm,use any SAR operated in continuous-flow mode,any SAR or SCBA with a full facepiece,or any air-purifying <br /> -aspirator with a full facepiece having a chin-style,front or back mounted organic vapor canister For emergency or nonroutine operations(cleaning <br /> spills reactor vessels,or storage tanks),wear an SCBA Warningf Atr-purifying respirators do not protect workers in oxygen-deficient atmospheres <br /> U respirators are used,OSHA requires a written respiratory protection program that includes at least. medical certification, training,fit-testing, <br /> periodic environmental monitoring,maintenance,inspection cleaning and convenient,sanitary storage areas Other Wear chemically protective <br /> i gloves boots,aprons,and gauntleu to prevent skin contact Polyvinyl alcohol with a breakthrough time of>8 hr Teflon and Viton are recorn ' <br /> I mended as suitable materials for PPE Ventilation Provide general and local exhaust ventilation systems to maintain airborne concentrations below <br /> the OSHA PELs(Sec 2)-Local exhaust ventilation is preferred because it prevents contaminant dispersion into the work area by controlling it at its - <br /> f source(103)Safety Stations Make available in the work area emergency eyewash stations,safety/quick-drench showers,and washing facilities <br /> Contaminated Equipment.Separate contanunated wort,clothes from street clothes and launder before reuse Remove toluene from your shoes and <br /> Clean PPE Comments Never eat,drink,or smoke in work arras Practice good personal hygiene after using this material especially before eating, <br /> drinking,smoking,using the toilet,or applying cosmetics <br /> -Section 9 Special Precautions and Comments <br /> Storage Requirements Prevent physical damage to containers Store in a cool,dry,well-ventilated area away from ignition sources and uneom- , <br /> paubles Outside or detached storage is preferred If stored inside use a standard flammable liquids warehouse room,or cabinet_To prevent static <br /> tpark.s electrically ground and bond all equipment used with toluene Do not use open lights in toluene areas Install Class 1 Group D electrical <br /> zquipment.Check that toluene is free of or contains < 196 benzene before use Engineering Controls To reduce potential health hazards use ' <br /> s--fficient dilution or local exhaust ventilation to control airborne contaminants and to maintain concentrauons at the lowest practical level Adminis <br /> i wito a Controls Adopt controls for confined spaces(29 CFR 1910 146)if entering areas of unknown toluene levels(holes,wells storage tanks) <br /> Consider preplacement and periodic medical exams of exposed workers that emphasize the CNS,liver kidney,and skin Include hemocyiometnc <br /> =zd thrombocyte count in cases where benzene is a contaminarnt of toluene Monitor air at regular intervals to ensure effective ventilation <br /> Transportation Data(49 CFR 172 101) ' <br /> DOT Shipping Name Toluene Packaging Authorizatloas QQuantity Limitations Vessel Stortiage Requirements <br /> DOT Hazard Class 3 a) Exceptions 150 a) Passenger Aircraft or Railcar 5L Vessel Stow age B <br /> €D 10 UN 1294 b) Non bulk Pachagan 202 b) Cargo Aircraft Only 160L Other -- <br /> I DOT Packing Group E c) Bulk Packaging 24� ' <br /> DOT Label Flammable Liquid <br /> Special Provisions(172 102) TI <br /> 1SDS Collection References 26 73 100 101 103 124 126 127 132 140 148 153 159 163 164 167 169 171 174 175 176 190 <br /> Prepared by M Gannon BA Industrial Hygiene Revlcµ PA Roy C11-1 MPii MedlC21 Res iew AC Darlington MD MPH ' <br /> rslyn�hs O 1942 by C uum W HuSns Corporu,oa Aar o _'..a a�pro��cucn w,lhwt tl+e p�bl ukda ram....00 u y,a6,�.aod 1lid .u to �+=.b�,ry of,nfo,m.i.m]rte,,.f.,r�i,�¢„rA...cl,p,upu.c, ,ro <br /> +znubil rcy u to the a�sa,r.cy r:ruat+hltry of..ch Infondt.on[a y-+pl ica non to�K purrlr.d. -��purto.o air far cct .q.,caacy a(w coo <br />