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:XTOXNET PIP - ESFENVALERATE Page 1 of 4 L, EXTOXNET Extension Toxicology Network Pesticide Information Profiles A Pesticide Information Project of Cooperative Extension Offices of Cornell University, Oregon State University, the University of Idaho, and the University of California at Davis and the Institute for Environmental Toxicology, Michigan State University. Major support and funding was provided by the USDA/Extension Service/National Agricultural Pesticide Impact Assessment Program. EXTOXNET primary files maintained and archived at Oregon State University Revised June 1996 Esfenvalerate Trade and Other Names: Trade names for the older fenvalerate compounds include Ectrin, Pydrin, Sanmarton, Sumifly, Sumiflower, and Sumitick. Trade names for the new product, esfenvalerate, include-Asana XL, Halmark, and Sumi-alfa. The compound may also be listed as S-fenvalerate. Regulatory Status: Most products containing esfenvalerate are General Use Pesticides (GUPs). The emulsified concentrate formulation is a Restricted Use Pesticide (RUP) because of possible adverse effects in aquatic organisms. Esfenvalerate is a moderately toxic pesticide in EPA toxicity class II; products containing it must contain the Signal Word WARNING on the label. Chemical Class: pyrethroid Introduction. Esfenvalerate is a synthetic pyrethroid insecticide which is used on a wide range of pests such as Y PY _ g moths, flies, beetles, and other insects. It is used on vegetable crops, tree fruit, and nut crops. It may be mixed with a wide variety of other types of pesticides such as carbamate compounds or organophosphates. Esfenvalerate has replaced the naturally occurring compound fenvalerate (to which it is almost identical) for use in the U.S. Much of the data for fenvalerate is applicable to the pesticide esfenvalerate because the two compounds contain the same components. The only differences in the two products are the relative proportions of the four separate constituents (isomers). Esfenvalerate has become the preferred compound because it requires lower applications rates than fenvalerate, is less chronically toxic, and is a more powerful insecticide. The compound contains a much higher of the one insecticidal) active isomer 84% for esfenvalerate and 22% for fenvalerate). I' percentage Y ( ) Formulation: It may be mixed with a wide variety of other types of pesticides such as carbamate compounds or organophosphates. Esfenvalerate has replaced the naturally occurring fenvalerate( to which it is almost identical) for use in the U.S. Much of the data for fenvalerate is applicable to the pesticide esfenvalerate because the two compounds contain the same components. The only differences in the two products are the relative proportions of the four separate constituents (isomers). Esfenvalerate has become the preferred compound because it requires lower applications rates than fenvalerate, is less chronically toxic, and is a more powerful insecticide. The compound contains a much higher percentage of the one insecticidally active isomer (84% for esfenvalerate and 22% for fenvalerate). Toxicological Effects: . Acute toxicity: Esfenvalerate is a moderately toxic compound via the oral route. The reported oral LD50 of esfenvalerate is 458 mg/kg in rats. It is slightly toxic via the dermal route, with a reported dermal LD50 of