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SU0006551 SSCRPT
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SU0006551 SSCRPT
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Entry Properties
Last modified
5/7/2020 11:32:31 AM
Creation date
9/6/2019 11:05:04 AM
Metadata
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EHD - Public
ProgramCode
2600 - Land Use Program
FileName_PostFix
SSCRPT
RECORD_ID
SU0006551
PE
2622
FACILITY_NAME
PA-0700214
STREET_NUMBER
14222
Direction
E
STREET_NAME
LOUISE
STREET_TYPE
AVE
City
RIPON
APN
20307035
ENTERED_DATE
5/8/2007 12:00:00 AM
SITE_LOCATION
14222 E LOUISE AVE
RECEIVED_DATE
5/8/2007 12:00:00 AM
P_LOCATION
99
P_DISTRICT
004
QC Status
Approved
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SJGOV\rtan
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\MIGRATIONS\L\LOUISE\14222\PA-0700214\SU0006551\SSC RPT.PDF
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EHD - Public
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EXTOXNET PIP - ORYZALIN %1_.0 Page 2 of 3 <br /> L <br /> exhibited decreased uterine and ovarian weights. Those exposed to doses of 75 mg/kg/day showed no observable <br /> effects [107]. <br /> • Reproductive effects: There were no adverse effects on reproduction in a three-generation study of rats fed dietary <br /> concentrations of 12.5, 37.5, or 112.5 mg/kg/day, the highest dose tested. Fetotoxic effects appeared at 12.5 <br /> mg/kg/day [58,107]. It does not appear that oryzalin causes reproductive effects. <br /> • Teratogenic effects: There were no birth defects in the offspring of pregnant rats fed dietary concentrations as high <br /> as 112 mg/kg/day for three generations, nor in the offspring of pregnant rabbits given doses of 125 mg/kg/day, the <br /> highest dose tested [8,107]. It appears that oryzalin is unlikely to cause teratogenic effects. <br /> • Mutagenic effects: Oryzalin was not mutagenic in several tests, including tests on live rats and mice and on <br /> bacterial cell cultures [107]. It does not appear that oryzalin is mutagenic. <br /> • Carcinogenic effects: When oryzalin was fed to rats in doses as high as 135 mg/kg/day for 2 years,there was an <br /> increase in the incidence of thyroid, mammary, and skin tumors [107]. Thyroid tumors and benign skin and <br /> mammary tumors occurred in rats fed a dietary level of 45 mg/kg/day for 2 years [107]. However,there were no <br /> tumors in mice fed doses as high as 548 mg/kg/day for 2 years [107]. Because of these conflicting results, it is not <br /> possible to assess the carcinogenicity of oryzalin. <br /> • Organ toxicity: Oryzalin has shown systemic effects on the thyroid, liver, and kidneys, as well as blood chemistry, <br /> in animal tests. <br /> • Fate in humans and animals: Oryzalin is moderately well-absorbed from the gastrointestinal tract, and rapidly <br /> metabolized and eliminated following absorption. When oryzalin was administered to male rats, 40%of the dose <br /> was excreted in the urine and 40%in the feces within 3 days. Similar results were obtained in tests with rabbits, a <br /> steer, and with Rhesus monkeys [106]. <br /> Ecological Effects: <br /> • Effects on birds: Oryzalin is slightly toxic to practically non-toxic to birds; the reported oral LD50 values in <br /> bobwhite quail and mallard ducks are greater than 500 mg/kg, and in chickens is 1000 mg/kg [1,58]. The 5-day <br /> dietary LC50 values in quail and mallard ducks are greater than 5000 ppm [8]. <br /> • Effects on aquatic organisms: Oryzalin is highly toxic to fish, with reported 96-hour LC50 values of 2.88 mg/L in <br /> bluegill sunfish, 3.26 mg/L in rainbow trout, and greater than 1.4 mg/L in goldfish fingerlings [8]. <br /> • Effects on other organisms: The reported oral LD50 for the compound in bees is 11 ug/bee, indicating it is <br /> nontoxic to bees [1,58]. <br /> Environmental Fate: <br /> • Breakdown in soil and groundwater: Oryzalin is of low to moderate persistence in the field,with reported field <br /> half-lives ranging from 20 to 128 days [58,11]. A representative value for soil half-life is estimated to be 20 days <br /> [11,58]. Microbial degradation is mainly responsible for the breakdown of oryzalin in soils, but it may undergo <br /> photodecomposition near the soil surface [58]. Volatilization is not appreciable [58]. Oryzalin is slightly soluble in <br /> water and it does not have a strong tendency to adsorb to soil particles [58,11]. It is bound to a greater extent with <br /> increasing soil organic matter and clay content. In soils with low proportions of these, high water tables and <br /> increased rainfall, oryzhn may be mobile, and thus present a risk of contamination to groundwater. <br /> • Breakdown in water: No breakdown of oryzalin by hydrolysis was observed at pH 5, 7, and 9 [8]. Based on its <br /> behavior in soil, breakdown by microbial processes is probably slow in the aquatic environment due to low levels of <br /> oxygen and low microbial activity. Photodegradation may be significant in the upper portions of the water column. <br /> • Breakdown in vegetation: Oryzalin is readily absorbed via the roots, and plant metabolism of oryzalin is minimal <br /> [58]. <br /> Physical Properties: <br /> http://extoxnet.orst.edu/pips/oryzalin.htm 3/26/2007 <br />
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