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EXTOXNET PIP- IPRODIONE Pagel of 3 <br /> EXTOXNET <br /> Extension Toxicology Network <br /> Pesticide Information Profiles <br /> A Pesticide Information Project of Cooperative Extension Offices of Cornell University, Oregon State University, the <br /> University of Idaho, and the University of California at Davis and the Institute for Environmental Toxicology, Michigan <br /> State University. Major support and funding was provided by the USDA/Extension Service/National Agricultural <br /> Pesticide Impact Assessment Program. <br /> EXTOXNET primary files maintained and archived at Oregon State University <br /> Revised June 1996 <br /> Iprodione <br /> Trade and Other Names: Trade names for commercial products containing iprodione include Chipco 26019, DOP <br /> 500F, Kidan, LFA 2043, NRC 910, Rovral, and Verisan. The compound is used in formulations with numerous other <br /> fungicides such as thiabendazole and carbendazim. It is compatible with most other pesticides. <br /> Regulatory Status: Iprodione is a slightly toxic compound and products containing it cavy the Signal Word <br /> CAUTION on the label. Most products containing iprodione are General Use Pesticides (GUPs). Chipco 26019 and <br /> Rovral (under some circumstances) may be Restricted Use Pesticides (RUPs). RUPs may be purchased and used only by <br /> certified applicators. <br /> Chemical Class: dicarboximide <br /> Introduction: Iprodione is a dicarboximide contact fungicide used to control a wide variety of crop diseases. It is used <br /> on vegetables, ornamentals, pome and stone fruit, root crops, cotton, and sunflowers to control fungal pests, and may also <br /> be used as a post harvest fungicide and as a seed treatment. Iprodione inhibits the germination of spores and the growth of <br /> the fungal mat (mycelium). <br /> Formulation: Not Available <br /> Toxicological Effects: <br /> • Acute toxicity: Iprodione is slightly toxic by ingestion, with reported oral LD50 values of 3500 mg/kg in rats, 4000 <br /> mg/kg in mice, and greater than 4400 mg/kg in rabbits [1,8]. No dermal toxic effects were noted at doses of over <br /> 2500 mg/kg in the rat and at 1000 mg/kg in the rabbit, indicating slight toxicity by this route [1,8]. Inhalation <br /> toxicity is also low for this compound. The 4-hour inhalation LC50 for iprodione is greater than 3.3 mg/L in the rat <br /> [8]. <br /> • Chronic toxicity: Rats given dietary doses of approximately 60 mg/kg/day over 1 1/2 years suffered no ill effects <br /> [1,8]. Dogs fed approximately 60 mg/kg/day over 18 months also showed no adverse effects [1,8]. In another study, <br /> http://extoxnet.orst.edu/pips/iprodion.htm 3/26/2007 <br />