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11. TOXICOLOGICAL INFORLWATION <br /> Skin: The LD50 for skin absorption in rabbits is>I0,000 mg/kg. <br /> Ingestion: The oral LD50 for rats is 20,000-34,000 mg/kg. <br /> Mutagenicity: In vitro mutagenicity studies were negative. Animal mutagenicity studies were negative. <br /> 12. ECOLOGICAL INFORMATION <br /> Movement & Partitioning: Based largely or completely on information for similar material(s), i.e., propylene <br /> glycol. Bioconcentration potential is low(BCF less than 100 or Log Pow less than 3). Log Wanol/water partition <br /> coefficient(log Pow)is—0.92. Henry Law Constant(H)is 1.2E-8 atm.m3/mole. <br /> Degradation & Transformation: Based largely or completely on information for similar material(s) i.e., <br /> propylene glycol. Biodegradation under aerobic static laboratory conditions is high (BOD20 OR BOD28/Th0D <br /> greater than 40%). Biodegradation is expected to be achievable in a secondary wastewater treatment plant_ 5-day <br /> biochemical oxygen demand (BODS) is 1.16 p/p. 200-day biochemical oxygen demand (BOD20) is 1.45 p/p. <br /> theoretical oxygen demand (THOD) is calculated to be 1.68 p/p_ Inhibitory concentration (IC50) in OECD <br /> Activated Sludge Respiration inhibition Test(OECD Test No.209) is greater than I gm/L. Degradation is expected <br /> in the atmospheric environment within minutes to hours. <br /> >Ecotoxicology: Based largely or completely on information for similar material(s),i.e,,propylene glycol. Material <br /> is practically non-toxic to aquatic organisms on an acute basis (LC50 greater than 100 mg/L in most sensitive <br /> species). <br /> Acute LC50 for fathead minnow(Pimephales promelas)is 4,600-54900 mg/L <br /> Acute LC50 for guppy(Poecilia reticulata)is greater than 10000 mg/L. <br /> Acute LC50 for water flea Daphnia magna is 4850-34400 mg/L <br /> Acute LC50 for rainbow trout(Oncorhynchus mykiss) is 44mL/L(about 44000 mg/L) <br /> 13. DISPOSAL CONSIDERA TIONS <br /> Waste Disposal Method; Landfill solids at permitted sites using registered transporters. Burn concentrated <br /> liquids,avoiding flameouts and assuring emissions comply with applicable regulations. Diluted aqueous waste may <br /> biodegrade,but avoid overloading plant biomass and assure effluent complies with applicable regulations. <br /> 4 <br /> S.Bravo Systems,Inc.Interstitial,Fluid <br />