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waw CEIMON Diesel Fuel' No. 2 Page 7 of S ADDITIONAL TOXICOLOGY DATA: r�ac Tht: data above is obtained from studies sponsored by the American Petroleum institute (API). 12. ADDITIONAL HEALTH DATA hDDITIONAL HEALTH DATA COMMENT: This product contains a mixture of petroleum hydrocarbons called middle distillates (which means they boil between approximately,350 aid 700 F) . Because of this broad description, many products are consideree middle distillates yet they are produced by a variety of different petroleum refining processes. Toxicology data developed on some middle cistillates found that they caused positive responses in some mutagenicity tests and caused skin cancer when repeatedly applied to mice over their lifetime. This product may contain some middle distillates found to cause those adverse effects. This product contains naphthalene. Overexposure to naphthalene by inhalation of vapor, ingestion or skin contact may produce sigis and symptoms of headache, fever, profuse sweating, nausea, abdominal pain, diarrhea, lethargy, tremors, convulsions, evidence of blood changes, including hematuria and hemoglobinuria, and optic neuritis. Laboratory animals given repeated oral doses of naphthalene have developer cataracts. MEDICAL CONDITIONS AGGRAVATED BY EXPOSURE TO NAPHTHALENE: individuals with congenital erythrocyte glucose-6-phosphate dehydrogenase: ceficiency may be particularly susceptible to the hemolytic effects of the naphthalene. Whole diesel engine exhaust was reviewed by the International Igency for Research on Cancer (IARC) in their Monograph 46 (1989). Eviderce for causing cancer was considered sufficient in animals and limiter in humans. IARC placed this material in category 2A, considering it proba) ly .carcinogenic to humans. The National Institute of Occupational Safety and Health (NIOS) ) has recommended that whole diesel exhaust be regarded as potentially causing cancer. This recommendation was based on test results showing increased lung cancer in laboratory animals exposed to whole diesel exhaust. The excess risk of cancer for people exposed to diesel exhaust has not been determined as studies on exposed workers have been inconclusive. It is recommended that exposure to diesel exhaust be minimized to reduce the potential cancer risk. -- The above information is based on the data of which we are aware and is believed to be correct as of the date hereof. Since the information contained herein may be applied under Conditions beyond our control and _ with which we may be unfamiliar and since data made available subsequent to the date hereof may suggest modification of the information,. we do not Revision Number: 10 Revision Date: 03/17/90 KSDS Number: 004525 NDA - No Data Available NA - Not Applicable