Laserfiche WebLink
Human Health Risk Assessment <br /> Fortner Mobil Oil Bulk Plant 04-343 <br /> 500 East Grant Line Road <br /> Tracy, California <br /> Reference Concentration and Reference Doses included central nervew system effects, and eye <br /> and nose irritation (Andersen et al., 1983; CHT, 1980; EPA, 1991). <br />' 4.2.2 Ethylbenzene <br /> ' The EPA calculated a subchronic and chronic Reference Concentration of 1 mg/m3 for <br /> ethylbenzene (EPA, 1991). Subchronic and chronic oral Reference Doses of 1 mg/kg-day and <br /> 0.1 mg/kg-day, respectively, were also established for ethylbenzene b) the EPA (EPA, 1991). <br /> The effect of concern considered in establishing the Reference Concentration and Reference <br /> Doses included developmental toxicity, hepatotoxicity, and nephrotoxicity (Andrew et al., 1981; <br /> ' Hardin et al., 1981; Wolf et al., 1956; EPA, 1991). <br /> ' 4.2.3 Xylenes <br /> ' Chronic and subchronic Reference Concentrations for mixed xyl.•aes have been set at <br /> 3 x 10-' mg/m3 (EPA, 1991). The EPA-established oral Reference Dk,e (RfD) for subchronic <br /> and chronic exposures are 4.0 mg/kg-day and 2.0 mg/kg-day, respectively (EPA, 1991). The <br /> effect of concern considered in establishing the Reference Concentration included central nervous <br /> system effects, throat irritation, and nose irritation (1--",jke et al., 1981; <br /> Litton Bionetics, 1978; EPA, 1991). <br /> 4.3 SUMMARY <br /> The chemicals selected for quantitative dose-response analysis .re benzene, toluene, <br /> ' ethylbenzene, and xylenes. Table 4-1 presents the health effects associated with potential <br /> inhalation to the four chemicals, the Cancer Slope Factor (for carcin,:genic effects); and the <br />• ' Reference Concentration (for noncarcinogenic effects). All criteria are derived from the <br /> Integrated Risk Information Service (IRIS, 1991) and the Health Effecs Assessment Summary <br /> ' Tables - FY-1991 (EPA, 1991). <br /> 30-0136-11 4-4 <br /> R <br />! 1 <br />