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<br /> M-VRON Regular Gasoline Page Z of 10
<br /> P-XYLENE(1,4-DIMETHYL BENZENE) 01,02,10,11,26,28,
<br /> M-XYLENE 01,02,10,11,14,15,17,18,26,28,
<br /> TOLUENE 01,02,10.11,14,15,17,18,26,28,
<br /> HEXANE 02,10,11,14,17,28,
<br /> CYCLOREXANE 01,02,10,11,14,17,26,28,
<br /> l.IETH'YL TERT BUTYL ETHER 01,10,11,24,26,
<br /> BENZENE 01,02,03,04,06,10,11,14,17,18,20,28,
<br /> TETRAETHYLLEAD 02,10,11,14,17,28,
<br /> O-XYLENE(1,2-DIMETHYL BENZENE) 0],02,10,11,14,15,17,18,26,28,
<br /> GASOLINE (GENERIC) 04,G8,14,15,17,16,20,
<br /> r
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<br /> REGULATORY LISTS:
<br /> 01-SARA 313 02-MASS RTK 03-NTP Carcinogen
<br /> 04-CA Prop. 65 05-M1 406 06-IARC Group L
<br /> 07-IARC Group 2A 08-IARC Group 2B 09-SARA 302/304
<br /> 10-PA RTK 11-NJ RTK 12-CERCLA 302.4
<br /> 13-MN RTK 14-ACGIH 'TLV 15-ACGIH STEL
<br /> 16-ACGIH Calculated TLV 17-OSHA PEL 18-OSHA STEL
<br /> 39-Chevron TLV 20-EPA Carcinogen 21-TSCA SECT 4
<br /> "- 22-TSCA SECT 5 SNUB 23-TSCA SECT 6 RULE 24-TSCA SECT 12 EXPORT
<br /> 25-TSCA SECT 8A CAIR 26-TSCA SECT 81) REPORT 27-TSCA SECT 81'
<br /> 28-Canadian WHMIS
<br /> Il. PRODUCT TOXICOLOGY DATA
<br /> EYE IRRITATION:
<br /> NDA. The hazard evaluation was based on data from similar materials_
<br /> SKIN IRRITATION:
<br /> This material was not a skin sensitizer in the modified Buehler Guinea Pig
<br /> Sensitization Test.
<br /> DERMAL TOXICITY:
<br /> NDA. The hazard evaluation was based on data frog% similar mat•eriais.
<br /> RESPIRATORY/INHALATION:
<br /> NDA. The hazard evaluation was based on data from similar materials.
<br /> INGESTION:
<br /> NDA. The hazard evaluation was based on data from similar materials.
<br /> ADDITIO14AL TOXICOLOGY DATh:
<br /> Lifetime inhalation of whole gasoline vapor has caused increased liver
<br /> tumors in female mice. The mechanism of this response is still being
<br /> investigated but it is thought to be an epigenetic process unique to the
<br /> female mouse. Inhalation exposure to whole gasoline vapor alsu caused
<br /> kidney damage and eventually kidney cancer in male rats.
<br /> No other animal model studied has shown these adverse kidney effects and
<br /> there is no physiological reason to believe that they would occur in man.
<br /> The cause of the kidney toxicity is thought to be due to the interaction
<br /> of isoparaffin hydrocarbons in the product with a specific serum protein,
<br /> alpha-2-microglobulin. Male rats synthesis large amounts of this Protein
<br /> —-- - -- -
<br /> which-is-filtered,- reabsorbed,-and-degraded_-by-_their kidneys.
<br /> rchhiraffins or their metabolites combine with this protein-an(] ma e i
<br /> ".undigestable" by the kidney proteases. With repeated exposures, the
<br /> - Revision Number: 13 Revision Date: 03/24/90 MSDS Number: OD0363
<br /> NDA - No Data Available NA -- Not Applicable
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