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accomplish two objectives: (1) account for the <br /> contribution from multiple media to total lead <br /> exposure; and, (2) provide a stronger scientific basis <br /> for determining a soil lead cleanup level at a specific <br /> site. <br /> Development of the IEUBK Model for OSWER use. During the 1989-91 <br /> time period, use of the EPA IEUBK model was identified as the <br /> best available approach for aceomplishing the objectives outlined <br /> in the August 1991 guidance. The model integrates exposure from <br /> lead in air, water, soil, dust, diet, and paint with <br /> pharmacokinetic modeling to predict blood lead levels in children <br /> (i.e. , children 6 to 84 months old) , a particularly sensitive <br /> population. <br /> In the spring of 1991, OSWER organized the Lead Technical <br /> Review Workgroup to assist Regional risk assessors and site <br /> managers in both using the model and making data collection <br /> decisions at CERCLA and RCRA sites. The workgroup was composed <br /> of scientists and risk assessors from the Regions and <br /> Headquarters, including the office of Research and Development <br /> (ORD) , and the Office of Pollution Prevention and Toxic <br /> Substances (OPPTS) . <br /> In November 1991, the EPA Science Advisory Board (SAB) <br /> reviewed the scientific merits of using the IEUBK model for <br /> assessing total lead exposure and developing soil lead cleanup <br /> levels at CERCLA and RCRA sites. In general, the SAB found the <br /> model to be an important advance in assessing potential hea:.'h <br /> risks from environmental contaminants. However, the SAB also <br /> recommended additional guidance on the proper use of the model. <br /> In response to SAB concern over the potential for incorrect <br /> use of the model and selection of inappropriate input values both <br /> for default and site-specific applications, OSWER developed a <br /> comprehensive Guidance Manual for the Integrated Exposure Uptake <br /> Biokinetic Model for Lead in Children" (referred to in this <br /> interim directive as the "Guidance Manual") . This Guidance <br /> Manual assists the user in providing inputs to the model to <br /> estimate risks from exposures to lead. It discusses the use of <br /> model default values or alternative values, and the application <br /> of the model to characterize site risks. Use of the Guidance <br /> Manual should facilitate consistent use of the IEUBK model and <br /> allow the risk assessor to obtain valid and reliable predictions <br /> of lead exposure. The Lead Technical Review Workgroup has been <br /> collecting data to further validate the model and to update the <br /> Guidance Manual as needed. <br /> Relationship to RCRA Corrective Action "Action" Levels. The <br /> approach for calculating 'a screening level for lead (including <br /> exposure assumptions) , set forth in this Revised Interim Soil <br /> Lead Directive, supersedes the guidance provided for calculating <br /> -6- <br />