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"'0. 318 Xylenc(Mixcd Isomers) 9142 _
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<br /> SectiohC Health Hazard Data anued
<br /> irregularity was reported in association wi[h workp ct exposure to xylene perhaps due to effects on liver lism.Xylene crosses the human
<br /> placenta,but docs not appear to be teratocnic under conditions tasted to dant. Medical Conditions Aggravated by Long-Term Exposure:CNS,
<br /> respiratory,eye,skin,gastrointestinal(Gig}, 'ver and kidney disorders. Target Organs:CNS,eyes,GIttract.liver,kidneys,and skin. Primary
<br /> Entry Routes:Inhalation,skin absorption(sli&ht),eye contact,ingestion. Acute Effects:Inhalation of high xylene concentrations may carie
<br /> lizziness;nausea,vomiting,and abdominal pain;eye,nose,and throat irritation;respiratory tract irritation leading to pulmonary edema(fluid in
<br /> lung);drowsiness;and unconsciousness.Direct eye contact can result in conjunctivitis and corneal burns.Ingestion may cause a burning sensation
<br /> in the oropharynx and stomach and transient CNS depression. Chrome Effects:Repeated or prolonged skin contact may cause drying and defat.
<br /> Ling of the skin leading to dermatitis.Repeated eye exposure to high vapor concentrations may cause reversible eye damage,periphc a]and central i
<br /> t neuropathy,and liver damage.Other symptoms of chronic exposure include headache,fatigue,irritability,chronic bronchitis,and GI disturbances
<br /> such as nausea,lou of appetite,and gas.
<br /> FIRST AID Emergency personnel should protect against exposure.Eyes:Do not allow victim to rub or keep eyes tightly shut.Gently lift eyelids
<br /> and flush irnmediatel and continuously with flooding amounts of water until transported to an emergency medical facility.Consult a physician
<br /> t immediately.SkIn:?uickJy remove contaminated clothing.Rinse with flooding amounts of water for at least 15 min.Wash exposed area with soap
<br /> and water.For reddened or blistered skin,consult a physician.Carefully dispose of contaminated clothing as it may pose a fare hazard.Inhalation:
<br /> Remove exposed person to fresh air and support breathing as needed.Monitor exposed person for respiratory distress'.Ingestion:Never give
<br /> anything by mouth to an unconscious or convulsing person.Contact a poison control center and unless otherwise advised,do not induce voiniting!If
<br /> spontaneous vomiting should occur,keep exposed person's head below the hips to prevent aspiration(breathing liquid xylene into the lungs).
<br /> i Aspiration of a few millimeters of xylene can cause chemical pnewwnNs.pulnwrrary edema,and hemorrhage. (Vote to Physicians:Hippuric acid
<br /> or the ether glucuronide of ortho-toluic acid may be useful in diagnosis of meta-,para- and ortho-xylene exposure,respectively.Consider gastric
<br /> lavage if a large quantity of xylene was ingested.Proceed gastric lavage with protzcuon of the airway from aspiration;consider endotracheal
<br /> r` intubation with inflated cuff.
<br /> IWC Section 7. Spill,Leak,and Disposal Procedures
<br /> Spill/Leak:Notify safety personnel,evacuate all unnecessary personnel,remove all heat and ignition sources,and ventilate spill area_Cleanup
<br /> � personnel should protect against vapor inhalation and skin err eye contact.If feasible and without undue risk stop leak.Use appropriate foam to
<br /> blanket release and suppress vapors.Watt spray may reduce vapor,but does not prevent ignition in closed spaces.For small spi7]s,absorb on paper
<br /> and evaporate in appropriate exhaust hood or absorb with sand or some non-combustible absorbent and place in containers for later disposal.For
<br /> large spills dike far ahead of liquid to contain.Do not allow xylene to enter a confined space such as sewers or drains.On land,dike to contain or .
<br /> divert to impermeable holding area.Apply water spray to control flammable vapor and remove material with pumps or vacuum equipment.On
<br /> water,contain mateial with natural barriers,booms,or weirs;apply universal gellingg agent;and use suction hoses to remove spilled material.
<br /> Report any release in excess of 1000 lb. Follow applicable OSHA regulations(29 Ci'R 1910.120). Environmental Transport: Little bioconcen.
<br /> trauon is expected.Biological oxygen demand 5(after 5 days at 20'C):0.64(no stated isomer).Ecoloxkity values: LDS Goldfish,13 m 4 hr,
<br /> conditions of bioassay not specified.no specific isomer. Environmental Degradation:In the atmosphere,xylenes degrade by reacting with
<br /> � Photnchcmically produced hydroxyl radicals with a half-life ranging from 1-1.7 hr.in the summer to 10-18 hr in winter or a typical bss of 67-86%
<br /> . per day.Xylenes are resistant to hydrolysis.Soll Absorption/Mobility:Xylenes have low to moderate adsorption to soil and when spilled on land,
<br /> will volatilize and leach into groundwater.Disposal:Asa hydrocarbon,
<br /> xylene is a good candidate for controlled incineration Contact your supplier
<br /> or a Iicensed contractor for detailed recommendations.Follow applicable Federal,state,and local regulations.
<br /> EPA Designations OSHA Designations
<br /> SARA Extremely Hazardous Substance(40 CFR 355):Not listed Listed as an Air Contaminant(29 CFR 1910.1000,Table Z-1-A)
<br /> Listed as a SARA Toxic Chemical(40 CFR 372.65)
<br /> Listed as a RCRA Hazardous Waste(40 CFR 261.33):No.U239,F003(spent solvent}
<br /> Listed as a CERCLA Hazardous Substance'(40 CFR 302.4):Final Reportable Quantity(RQ),l OtJO lb(454 kg)(•per Clean Wates Act,
<br /> 1 Sec.31l(b)(4);per RCRA,Sec.30011
<br /> Section 8. Special Protection Data
<br /> Goggles:Wear protective eyeglasses or chemical safety goggles,per OSHA eye.and face-protection reguladoru(29 CFR 1910.133).Because
<br /> contact lens use in industry is controversial,establish your own policy.Respirator.Seek professional advice prior to respirator selection aid use.
<br /> Follow OSHA respirator regulations(29 CFR 1910.134)and,if necessary.wear a MSHAM10SH-approved respirator.For concentrations>1000
<br /> ppm,use any chemical cartridge respirator with organic vapor cartridges;any powered,air-purifying respirator with or48nic vapor cartridges;any
<br /> supplied-air respirator,or any self-contained breathing apparatus.For cm,6rgency or nonroutine operations(cleaning spills,Tractor vessels,or
<br /> storage tanks),wear air SC$A.Warrting!Air-purifying ntupiralors do not protect workers in oxygen-drfrcienl atmospheres..If respirators ere us_ed.,,
<br /> F Other:Wear chemically protective g)oves,boots,aprons,and gauntlets to prevent all skin contact.With breakthrough Lima>8 hr,consider
<br /> polyvinyl alcohol and fluorocarbon rubber(Vicon)as materials for PPE.VentUation:Provide general and local exhaust ventilation systems to
<br /> maintain airbome concentrations below the OSHA PFls(Ser.2).Local exhaust ventilation is preferred be-use it prevents wntaminant dispersion
<br /> into the work area by controlling it at its sours clef Safety Stations:Make avar7able in the work arra emergency eyewash stations,safety/quick-
<br /> drench showers,and washing facilities.Contamlaated Equipment:Separate contaminated work clothes from street clothes.Launder contami-
<br /> 1 r nated work clothing before wearing. cmove this material from your shoes and clean PPE.Comments:Never eat,drink,or smoke in work areas.
<br /> Practice good personal hygiene after using this material,espocially before eating,drinking,smoking.using the toiled or applying cosmetics.
<br /> Section 9. Special PrecautionS and Comments
<br /> Storage Requirements:Store in clearly labelled,tightly closed,containers in a cool,well-ve►tilamd place,away from strong oxidizing materials
<br /> 1. 1 and heat and ignition sources.During transferring operations,electrically ground and bond metal containers. Engineering Controls:To reduce
<br /> potential health hazards,use sufficient dilution or kxud exhaust ventilation to control airborne contaminants and to maintain concentrations at the
<br /> lowest practical level.Use hermetically sealed equipment,transfer xylene in enclosed systems,avoidpr�eases associated with open evaporating
<br /> surfaces,and provide sources of gas release with enclosures and local exhaust ventilation.Use Clan L Group D electrical equipment_Ad ministra
<br /> tive Controls:Establish air and biological monitoring programs and evaluate regularly.Consider preplacement and periodic medical examinations
<br /> including a complete blood count,a routine urinalysis,and liver function tests.Consider hematologic studies if there is any significant contamination
<br /> of the solvent with benzene-If feasible,consider the replacement of xylene by las toxic solvents such as petrol(motor fuel)or white spirit.Before
<br /> carrying out maintenance and repair work steam and flush all equipment to remove any xylene residues.
<br /> Transportation Data(49 CFR 172.101)
<br /> DOT Shipping Same:Xylenes Packaging Authorizations Quantity Limitations Vessel Stowage Requirements
<br /> DOT Hazard Class:3 a) Exceptions: 173.150 a)Passenger,Aircraft,or Railcar:5L a)Vessel Stowage:B
<br /> ID No.:UN 1307 b)Nonbulk Packaging: 173.202 b)Digo Aircraft Only:64L b)Other —
<br /> DOT Packing Group:Il c)Bulk Packaging: 173.242
<br /> i I DOT Label:Flammable Liquid
<br /> Special Provisions(172.102):Tl
<br /> M5D5 Collection References:26,73,89,100,101,103,124, 126,127,132, 133,136,139,140,148,149,153, 159,163,164,167,171,174,176,180.
<br /> Prepared by:MJ Wurth,BS:Industrial Hygiene Review:PA Rory,MPII,CI1-I:Medinr Review:W Sil
<br /> verman,MD
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