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Section b. Health Hazard Data
<br /> lZecertly,'studies showed that TEL is rust mctabep to¢icthyl lead. then over a period of months,comto inorganic lead which is then
<br /> �. deposited in bone.At this point chronic effects co resemble those caused by direct exposure to inorganiPWnd. if victim sur-vivcs en acute
<br /> exposure,recovery may take weeks to months.It is questionable whether all changes are reversible following heavy or long-term exposures.
<br /> Teratogenic effects may occur,'a syndrome with severe menta!retardation has been seen among children of heavy gasoline sniffers.tt36) l
<br /> Medical Conditions Aggravated by Long-Term Exposure: Mental disorders and hypertension. Target Organs: CICS,cardiovascular
<br /> ysiem,eyes,•liver,kidneys. Primary Entry Routes: Eye,skin, inhalation,ingestion. Acute Effects:The primary Largo organ is the brain,and
<br /> 'NS effects occur in three categories; mild,moderate,and severe.Mild effects include anxiety,irritability,insomnia, lurid dreams,vomiting,
<br /> ctallic taste,paleness,cerebellar ataxia,and diarrhea. Moderate effects are disbrienlation,hyperexcitability.Lremors,chorea(involuntary,`
<br /> incoordination of face and limbs),bradycardia(slow heart action),hypotension(abnormally low blood pressure),and hypoLhcrmia(lowered
<br /> body temperature).Severe symptoms include delusions,hallucinations,mania,convulsions,cerebellar edema(fluid in the brain),coma,and
<br /> death.Ringing in the ears,impaired vision(due to weakening of the eye muscles),elevated liver enzymes,and anemia may also occur. Chronic
<br /> Effects:May occur once TEL is metabolized to inorganic lead.Symptoms include anemia,appetite loss,weakness,insomnia, muscle and joint
<br /> pain,and colic accompanied by severe abdominal pain.See Genium MSDS No.713.
<br /> FIRST AID Eyes:Do not allow victim to rub or keep eyes tightly shut-Gently lift eyelids and flush immediately and continuously with
<br /> flooding amounts of water until transported to an emergency medical facility.Consult a physician immediately. Skin:Quickly remove contami-
<br /> nated clothing.Rinse with flooding amounts of water for at]east 15 min.Wash exposed area with soap and water.For reddened or blistered
<br /> skin,consult a physician.Inhalation:Remove exposed person to fresh air and support breathing as needed.ingestion: Never give anything by
<br /> mouth to an unconscious or convulsing person.Contact a poison control center an unless otherwise advised,have that conscious and alert,
<br /> person drink 1 to 2 glasses of water to dilute.Induce vomiting only if large amounts are ingested.Note to Physicians: Urine lead levels are
<br /> better indicaLors'of exposure than blood lead levels.Blood lead levels may not reflect exposure until toxicity is severe where as urine directly
<br /> reflects amount of exposure.In severe acute toxicity,urine lead levels are usually>350 gg/L but blood levels are<50 gg/L.Chelation theiapy
<br /> can be useful for chronic exposure but not for acute_.If blood levels are greater than 50}µg/dL begin chelation therapy with BAL.calcium
<br /> EDTA,or D-penicillamine
<br /> Section 7. -Spill,'Leak, and Disposal Procedures
<br /> Spill/Leak:Notify safety personnel, isolate and ventilate area,deny entry,and stay upwind.Shut off ignition sources.For small spills,take,up
<br /> with eanh,sand,vermiculite or charcoal absorbent(decreases evaporation)and place in suitable containers.Dike far ahead of large spill,neutral-
<br /> ize with agricultural(slaked)lime,sodium bicarbonate,or crushed limestone and adjust to pH 7.Investigate reclamation or disposal.Follow
<br /> applicable OSHA regulations(29 CFR 1910.120). Ecotoxicity Values:Bluegill,TLm=2, 1.4,and 0.2 mg/L.at 24,48,and 96 hr,respectively.
<br /> r.Environmental Degradation:In the atmosphere.TEL rapidly degrades by reaction with photochcmically produced hydroxyl radicals and ozone
<br /> i molecules.The half-life is-- 1.5 to 5 hr depending on solar intensity.In water.volatilization is expected. Half-life from a model river is 5.3 hr and
<br /> 3 days in a model pond.It is also subject to hydrolysis and direct photolysis.Some TEL may degrade into dialkyl and trialkyl lead which may be
<br /> more resistant in water than TEL itself.Bioaccumuladon may occur in aquatic organisms.If released to soil,some TEL is expected to degrade to
<br /> water soluble compounds and leach,although some may volatilize or undergo direct photolysis if exposed to sunlight.Disposal:Contact'your
<br /> t. supplier or a licensed contractor for detailed recommendations. Follow applicable Federal,state, and local regulations.
<br /> EPA Designations OSHA Designations
<br /> Listed(as lead compounds)as a SARA Toxic Chemical(40 CFR 372.65) Listed as an Air Contaminant(29 CFR 1910.1000,Table"Z-1-A)
<br /> Listed as a SARA Extremely Hazardous Substance(40 CFR 355),TPQ: 100 ibs
<br /> isied as a RCRA Hazardous Waste(40 CFR 261.33): P110
<br /> ' E isted as a CERCLA Hazardous Substance' (40 CFR 302.4): Final Reportable Quantity(RQ), 10 lb(4.54 kg) ['per RCRA.Sec.3001 &:CWA,
<br /> Sec.311 (b)(4)1
<br /> -,-Sect ion 8. Special Protection Data
<br /> Goggles:Wear protective eyeglasses or chemical safety goggles,per OSHA c)-c-and face-protection regulations(29 CFR 1910.133).Because
<br /> contact lcns use in industry is controversial,establish your own policy.Respirator: Seek professional advice prior to respiralar Selection and use.
<br /> Follow OSHA respirator regulations(29 CFR 1910.134)and, if necessary,vicar a MSHA/NIOSH-approve-d respirator.For<0.75 mg/m3.use
<br /> any supplied-air respirator(SAR)or SOBA.For<1.875 mg/m3,use any SAR operated in continuous-flow mode.For<3.75 mg/m3,use any
<br /> SOBA or SAR with a full facepiece or a SAR with a tight fitting facepiece operated in continuous-flow mode.For<40 mg/m3,use any SAR
<br /> operated in pressure-demand or other positive pressure mode. For emergency or nonroutine operations(cleaning spills,reactor vessels,or storage.
<br /> tanks),wear an SCBA.Warning?Air-purifying respirators do not protect workers in oxygen-deffcienr atmospheres.if respirators arc used.OSHA
<br /> requires a respiratory protection program that includes at least;medical cenifieadon,training,ret-testing,periodic environmental monitoring.
<br /> i maintenance,inspection,cleaning,and convenient.sanitary storage areas.Other:Wear chemically protective gloves,boots,aprons,and gauntlet
<br /> to prevent skin contact.Do not use rubber as material for PPE(TEL may degrade rubber).Ventilation:Provide general and local exhaust vcndla-
<br /> tion systems to maintain airborne concentrations below OSHA PEL(Sec.2).Local exhaust ventilation is preferred because it prevents eontami-
<br /> zaant dispersion into work area by controlling it at the source!")Safety Stations:Make available in the work area emergency eyewash stations,
<br /> lsafety/quick.drench showers,and washing facilities.Contaminated Equipment:Separate contaminated work clothes from street clothes and
<br /> launder before reuse.Remove this material from your shoes and clean PPE.Comments: Never eat,drink,or smoke in work areas.Practice good
<br /> persona)hygiene after using this material,especially before eating,drinking,smoking,using the toiled or applying cosmetics.
<br /> -Section 9. Special Precautions and Comments
<br /> f Storage Requfrements:Store in a cool,dry,dark,well-ventilated area(equipped within automatic Sprinkler system)away from heat,ignition
<br /> sources,and incompatibles(Sec.5).Keep containers tightly closed:exposure to air can lead to explosive decomposition.Engineering
<br /> Controls:To reduce potential health hazards,use sufficient dilution or local exhaust ventilation to control airborne contaminants and to
<br /> tmammin conccntrations at the lowest practical level.Use nonsparking tool for any maintenance procedures.Administrative Controls:
<br /> :Consider preplacement and periodic medical exams of exposed workers with emphasis on the CNS,including personality changes.For greater
<br /> assurance of individual protection-monitor urinary output of exposed workers.
<br /> Transportation Data(49 CFR 172.101)
<br /> i DOT Shipping Name:Terraethyl lead,liquid Packaging Authorizations Quantity Limitations
<br /> DOT Hazard Class: 6.1 a)Exceptions:None a)Passenger Aircraft or Railcar:Forbidden
<br /> ID No.:NA 1649 b)Non-bulk Packaging: 173.201 b)Ca bo Aircraft Only: Forbidden
<br /> OT Packing Group:I c) Bull:Packaging:None Vessel Stowage Requirements
<br /> T Label: Poison, Flammable liquid a) Vessel Sto«•age: E
<br /> pecial Provisions(172.IO2): — b) Other:40
<br /> tlSDS Collection References:23,73,99.101. 103, 1'_4,126. 127, 132,136, 140, 148.149,153. 159,167.,163, 164,167, 17,.175
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