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EXHIBIT 4-1 <br /> STANDARD DEFAULT FACTORS <br /> Symbol Definition fundal Default Reference <br /> CSFo Cancer slope factor oral(mi;/kg-d)-1 — IRIS,HEAST,or NCEA <br /> CSFI Cancer slope factor Inhaled (mgfkg-d)-1 — IRIS,HEAST, or NCEA <br /> RfDo Reference dose oral(mg/kg-d) — IRIS,HEAST, or NCEA <br /> RIDI Reference dose inhaled (mg/kgd) — IRIS,HEAST,or NCEA -- <br /> TR Target cancer risk <br /> THO Target hazard quotient <br /> BWa Body weight,adult(kg) 70 RAGS(PartA), EPA 1989(EPA/540/1-89=2) ' <br /> 8Wc Body weight,child (kg) 15 Exposure Factors , EPA 1991 (OSWER No.9285.6-03) <br /> ATc Avenging time-carcinogens(days) 25550 RAGS(Part A), EPA 1889(EPA1540/1.89/002) <br /> ATn Averaging time-noncarcinogens(days) ED'365 <br /> SAa 25%Surface area,adult(cm2lday) 5000 Dermal Assessment,EPA 1992 (EPA160018-91/0118) <br /> SAc 25% Surface area,child (cm'lday) 2000 Dermal Assessment,EPA 1992(EPA/6008.910118) <br /> AF Adherence factor(mg/an) 02 Dermal Assessment, EPA 1992(EPA/60(U8-01011 B) <br /> ASS Skin absorption (unitless): <br /> —organics 0.1- PEA,Cat-EPA(DISC, 1994) <br /> —Inorganics 0.01 PEA,Cat-EPA(OTSC, 1994) <br /> IRAs Inhalation rate-adult(m'/day) 20 Exposure Factors ,EPA 1991 (OSWER No.9285.6-03) - <br /> IRAc Inhalation rate-child (m'/day) 10 RAGS(PartA), EPA 19119(EPA1540/1-89=) <br /> IRWa Drinking water ingestion-adult(Qday 2 RAGS(Part A), EPA 1989(EPA/54011-89A102) <br /> IRWc Drinking water ingestion-child (Qday) 1 PEA,Cal-EPA(OTSC,1994) <br /> IRSa Sol Ingestion-adult(mg/day) 100 Exposure Factors, EPA 9991 (OSWER No.9285.6-03) <br /> IRSc Sol ingestion-child (mg/day), 200 Exposure Factors, EPA 1991 (OSWER No.9285.6-03) <br /> IRSo Sol Ingestion-occupational(mg/day) 50 Exposure Factors ,EPA 1991 (OSWER No.9285.6-03) <br /> EFf Exposure frequency-residential(d1y) 350 Exposure Factors , EPA 1991 (OSWER No.9285.6-03) , a <br /> EFo Exposure frequency-occupational(dty) 250 Exposure Factors , EPA 1991 (OSWER No.9285.6-03) <br /> EOr Exposure duration-residential(years) 304 Exposure Factors , EPA 1991 (OSWER No.9285.6-03) <br /> EDc Exposure duration-child (years) 6 Exposure Factors , EPA 1991 (OSWER No.9285.6-03) <br /> EDo Exposure duration-occupational(years) 25 Exposure Factors ,EPA 1991 (OSWER No.9285.6-03) <br /> Age-sd)usted factors for carcinogens: <br /> IFSsd) Ingestion factor,soils QmgyrKkg*dD 114 RAGS(Part 5).EPA 1991 (OSWER No.9285.7-01B) <br /> SFSad) Skin contact factor,sails amgy Kkg-dD 503 By analogy to RAGS(Part B) <br /> InhFad) Inhalation factor((m'yr)1kg-d)) 11 By analogy to RAGS (Part 8) <br /> IFWad) Ingestion factor,water(Vyry(kg-dD 1.1 By analogy to RAGS (Part 8) <br /> VFW Volatilization factor for water(Um) OA RAGS(Part 8) , EPA 1991 (OSWER No.9285.7-01B) <br /> PEF Particulate emission factor(m'Atg) See below Sol Screening Guidance (EPA 1996a,b) <br /> VFs Volatilization factor for sod(m IA M See below Sol Screening Guidance (EPA 1996a,b) <br /> sat Sol saturation concentration(mgrkg) See below Sol Screening Guidance (EPA 1996a,b) -' <br /> Footnote: <br /> 'Exposure duration for lifetime residents is assumed to be 30 years total. For carcinogens, exposures are combined for children(6 yea <br /> and adults (24 years). <br /> 16 <br />