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i Occupational Health Guideline for Xylene ti INTRODUCTION • Efl'eets of CWfteqXWWe This guideline is intended as a source of information for L Sltorr-term F-VMNra Xylene vapor may cause itrrta- em to ees, employers, tion of the eyes, nose, and throat. At high concentsa- P Y P Yom,PhYnasas,industrial hygienists, tions,xylene vapor may cause severe breathing diffical- and other occupational health profemonals who may tea which may be delayed in onset. At high oanemtra- k have a need for such information.It does not attempt to tion, it may also catnse present all data;rather,it presents pertinent informatmn nese, and In addition, breathing high and data in summary form. Ontratsom may cause Ions of appetite„nuns, von. 1 � ' SUBSTANCE IDENTIFICATION iting,and abdominal pain. Liquid xylene my be uT=. Ing to the eyes and skin. Exposure to high eoncentra. • Formula:C.H.(CFL), tinea of xylene vapor my Caine reversible damage to 1 the kidneys and liver. • SynonY"if Commercial xylene (xylol) is a mixture, 2 LONS-ierss Egmswv Repeated or prolonged expo. mostly the meta-isomer. 1)O-xylene, Ortho-xYlene. 1.2- sure to rylsae may cense a skin rash.Repeated exposim ��Ir dtmethylbeazene;2)m-xylene,meta-xylem, l,34imeth- of the eyes to high vosnanuations of xylene vapor may Ylbanzene; 3) p-xylene, para-xylene, 1,44nmethylben- cause revc=snble eye damage. zene A Rgwnft SISM gad SYmptosw A physician.ahoWd be �c Appearance and odor. Colorless liquids with aroma- contacted if anyone develops any signs or symptm odon(pure p-rykne is a solid below 12.7 C(SS F)). gad suspects that they are caused by cgxxum to xylme. ` • Raeomseaded medleal ranee PERMISSIBLE EXPOSURE LIMIT (PEL) The following medical procedum should be tirade The current OSHA standard for xylene a I00 parts of available to each employee who aexposed to xylene at xylene per million poteatiallY hazardous levels. parts of air(ppm)averaged over an L Ir�al Msidic+al F.ia�u+satiar: f I eight-hair works shift Thin may alio be as 435 --A complete history and Physical exammatson:'The +� milligrams of xylene per cubic meter of aur (=VMS). PmWw is. to detect PmIeaiatting conditions.that might 1VIOSH has recommended that the pe m>r=-W expo- Place the_ employee at increased nskc, and to ii sure limit be changed to 100 ppm averaged over a work establish mon shndt of up to tea hours per day, forty homn per week, nation of the central nervous baseline for fiftre stealth synem'eyes, risme.Frxsmi- with an acceptable coking level of 200 ppm av=Sed nilSNUO ti - over a 10•munute pend. The NIOSH Cntem Dodi- tract, blood, liver, and kidneys should be strewed. .. meat for Xylene should be consulted for more detailed skin should be examined for evidence of shiners tea► mformatraa. A complete blood count: Xylene has been shown HEALTH HAZARD INFORMATION to cause revenWe hm top glen A complete blood couM std be�1°am ah. irag a red MD cot, a white cell Roam of azpoan+e cximat of a stained Must, a di$erentiai Xylem can affect the body if it is inhaled,if it comes m smear, as wdl as hemoglobin and contact with the �ato�' may eyes or skin, or hf it is swallowed. it —Liver fm wdm teas:; Since liver damage has been Y eater the body through the sarin. observed is humans exposed to xylene,a prcae of liver Those rem." widakwis irefirct good indnsstrW hypiaro and isrns+dcal sirveiflt nm f j1 asaat in achevrnQ an eiteetfw oceupa6oft huM Wqpam wilh al mend of OSHA,i��not be � �ac� � UA oEPARTUM of NMTH AND WJWW son"= l� as hems s o�. W Gonad 0="***UA W 8�4iir M Adop m aa+aa+bna! Scary and f+sMh i 8*P"+nbW 1078