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has prohibited any skin contact with the substance. <br />Among mice, 96 percent of the males and 98 percent of <br />the females on the higher dose developed gastric cancer. <br />No safe level for exposure to DBCP exists. <br />OSHA has selected for the purposes of this discussion <br />a level of 20 million sperm per milliliter ejaculate below <br />which a man is_to_be considered oligospermic. Based on the <br />above evidence OSHA concludes that exposure to DBCP has been <br />demonstrated to produce infertility (reduced sperm count) and <br />sterility in male workers at very low levels of exposure. <br />The long latency periods involved in carcinogenesis <br />make it difficult to demonstrate that an exposure level which <br />appears not to induce cancer in the short run is in fact <br />safe; 5-40 years may be required before exposure to a <br />carcinogen might produce detectable cancers. A substance <br />which causes cancer in animals must be considered as posing a <br />carcinogenic risk to workers. <br />Due to the extremely serious nature of the hazard of <br />exposure to DBCP, the concentration of DBCP formulating <br />operations in those companies capable of providing the <br />necessary protection for their employees is desirable and <br />necessary. <br />Health Hazard: Routes of entry: Employees may be <br />exposed through inhalation (breathing); through ingestion <br />(swallowing); through skin contact. Overexposure may cause <br />damage to lungs, liver or kidne-.-3. <br />DBCP must never be allc --�d to remain on the skin. <br />Clothing and shoes must not bE- allowed to become contaminated <br />with DBCP, and if they do, they must be promptly removed and <br />2 <br />