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SAFETY DATA SHEET WH <br /> ISSUED: 1� <br /> .41CARDINA L <br /> REFERENCE: il-TO0T009 <br /> Germ cell mutagenicity In vivo tests showed mutagenic effects <br /> Germ cell mutagenicity -AMES test- S. Positive <br /> typhimurium <br /> Germ cell mutagenicity -AMES test- Positive <br /> mouse- male <br /> IARC No component of this product present at levels greater than or equal to <br /> 0.1%is identified as a probable, possible or confirmed human carcinogen <br /> b IARC <br /> ACGIH No component of this product present at levels greater than or equal to <br /> 0.1% is identified as a carcinogen or potential carcinogen by ACGIH <br /> NTP No component of this product present at levels greater than or equal to <br /> 0.1% is identified as a known or anticipated carcinogen by NTP <br /> OSHA No component of this product present at levels greater than or equal to <br /> 0.1% is identified as a carcinogen or potential carcinogen by OSHA <br /> Reproductive toxicity No data available <br /> Specific target organ toxicity - single No data available <br /> exposure <br /> Specific target organ toxicity - repeated No data available <br /> exposure <br /> Aspiration hazard No data available <br /> Additional information To the best of our knowledge, the chemical, physical, and toxicological <br /> properties have not been thoroughly investigated <br /> Aluminum Oxide 1344-28-1 <br /> Acute toxicity - LD50 -oral - rat > 10,000 m /k <br /> Acute toxicity - LC50 - inhalation - rat > 2.6 m L/4 h <br /> Acute toxicity - dermal No data available <br /> Skin irritation - rabbit No skin irritation <br /> Eye irritation - rabbit No e e irritation <br /> Respiratory or skin sensitisation - DId not cause sensitisation on laboratory animals <br /> maximisation test- guinea pig <br /> Germ cell mutagenicity No data available <br /> Carcinogenicity This product is or contains a component that is not classifiable as to its <br /> carcinogenicty based on its IARC ACGIH NTP or EPA classification <br /> IARC No component of this product present at levels greater than or equal to <br /> 0.1% is identified as a probable, possible or confirmed human carcinogen <br /> b IARC <br /> NTP No component of this product present at levels greater than or equal to <br /> 0.1% is identified as a known or anticipated carcinogen by NTP <br /> OSHA No component of this product present at levels greater than or equal to <br /> 0.1% is identified as a carcinogen or potential carcinogen by OSHA <br /> Reproductive toxicity No data available <br /> Specific target organ toxicity - single No data available <br /> exposure <br /> Specific target organ toxicity - repeated No data available <br /> exposure <br /> Aspiration hazard No data available <br /> Additional information Cough, chest pain, difficulty in breathing, astrointestinal disturbance <br /> Addittional information Liver irregularities based on human evidence <br /> Amorphous Silica 112926-00-8 <br /> Acute toxicity no data available <br /> Acute toxicity: Inhalation no data available <br /> Acute toxicity: Dermal no data available <br /> Skin irritation no data available <br /> Eye irritation no data available <br /> Respiratory or skin sensation no data available <br /> Germ cell mutagenicity no data available <br /> Carcinogenicity., IARC: Group 3: not classifiable as to its carcinogenicity to humans <br /> ACGIH no component of this product present at levels greater than or equal to <br /> 0.1% is identified as a carcinogen or potential carcinogen by ACGIH <br /> NTP no component of this product present at levels greater than or equal to <br /> 0.1% is identified as a known or anticipated carcinogen by NTP <br /> OSHA no component of this product present at levels greater than or equal to <br /> 0.1% is identified as a carcinogen or potential carcinogen by OSHA <br /> Reproductive toxicity no data available <br /> Specific target organ toxicity - single no data available <br /> exposure <br /> Page 4 of 12 <br />