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SKIN IRRITATION: Ratings corresponding to the following definitions are derived from data obtained from the test <br />methods as described in the 16 CFR 1500.41 and categories of toxicity as described in NAS Publication 1138: <br />1. Practically Non -irritating: The undiluted product may cause mild or slight irritation (erythema skin reaction <br />values of 0 or 1) of the intact or abraded skin of rabbits at 72 hours. EPA Category IV. <br />2. Moderate Irritant.The undiluted product causes moderate irritation (erythema skin reaction values of primarily <br />1 and/or 2) of the intact or abraded skin -of rabbits at 72 hours. EPA Category 111. <br />3. Severe Irritant: The undiluted product causes severe irritation (erythema skin reaction values of primarily 3 or 4 <br />with or without edema) of the intact or abraded skin of rabbits at 72 hours. EPA Category 11. <br />4. Corrosive: The undiluted product causes visible destruction, irreversible alterations, or scarring of the tissue <br />structure at the sight of contact on the intact or abraded skin of rabbits. EPA Category I. <br />EYE IRRITATION: Ratings corresponding to the following definitions are derived from data obtained from the test <br />methods described in the 16 CFR 1500.42 and categories of toxicity as described in NAS Publication 1138: <br />1. Practically Non -Irritating: The undiluted product, when instilled into the eyes of rabbits, produces minimal <br />effects, clearing in less than 24 hours. EPA Category IV. <br />2. Moderately Irritating: The undiluted product, when instilled into the eyes of rabbits, produces corneal involve- <br />ment or irritation, clearing in 7 days or less. EPA Category Ill. <br />3. Severely Irritating: The undiluted product, when instilled into the eyes of rabbits, produces corneal involvement <br />or irritation, clearing in 21 days or less. EPA Category 11. <br />4. Corrosive: The undiluted product, when instilled into the eyes of rabbits, produces irreversible destruction of <br />ocular tissue or corneal involvement or irritation persisting for more than 21 days. EPA Category 1. <br />ORAL TOXICITY: Ratings corresponding to the following definitions are derived from data obtained from the test <br />methods as described in the 16 CFR 1500.40 and categories of toxicity as described in 40 CFR 162.10: <br />1. Non -Toxic: The probable lethal dose of undiluted product to 50% of the test animals determined from ingestion <br />studies (LD„) is greater than 5 grams per kilogram of body weight. EPA Category IV. <br />2. Slightly Toxic: The probable lethal dose of undiluted product to 50% of the test animals determined from inges- <br />tion studies (LD„) is greater than 500 milligrams per kilogram and less than or equal to 5 grams per kilogram of <br />body weight. EPA Category 111. <br />3. Moderately Toxic: The probable lethal dose of undiluted product to 50% of the test animals determined from <br />ingestion studies (LD„) is greater than 50 milligrams per kilogram and less than or equal to 500 milligrams per - <br />kilogram of body weight. EPA Category Il. <br />4. Very Toxic: The probable lethal dose of the undiluted product to 50% of the test animals determined from inges- <br />tion studies (LD,,) is less than or equal to 50 milligrams per kilogram of body weight. EPA Category 1. <br />DERMAL TOXICITY: Ratings corresponding to the following definitions are derived from data obtained from the <br />test methods as described -in 16 CFR 1500.40 and categories of toxicity as described in 40 CFR 163.100-4: <br />1. Non -Toxic: The probable lethal dose of undiluted product to 50% of the test animals determined from dermal <br />toxicity studies (LD„) is greater than 2 grams per kilogram of body weight with no mortality observed when this <br />dose is administered. EPA Category IV. <br />2. Slightly Toxic: The probable lethal dose of undiluted product to 50% of the test animals determined from dermal <br />toxicity studies (LD„) is greater than 2 grams per kilogram of body weight, although some mortality is observed <br />at this dose level. EPA Category ill. <br />3. Moderately Toxic: The probable lethal dose of undiluted product to 50% of the test animals determined from <br />dermal toxicity studies (LD„) is greater than 200 milligrams and less than or equal to 2 grams per kilogram of <br />body weight. EPA Category Il. <br />4. Very Toxic: The probable lethal,dose of undiluted product to 50% of the test animals. determined from dermal <br />toxicity studies (LD„) is less than or equal to 200 milligrams per kilogram of body weights. EPA Category 1. <br />INHALATION TOXICITY: Ratings corresponding to the following definitions are derived from categories of toxic- <br />ity described in 40 CFR 162.10: <br />1. Non -Toxic: The probable lethal dose of undiluted product to 50% of the test animals determined from inhalation <br />studies (LC„) is greater than 20 milligrams per liter by volume when inhaled continuously for one hour or less. <br />EPA Category IV. <br />2. Mildly Toxic: The probable lethal dose of undiluted product to 50% of the test animals determined from inhala- <br />tion studies (LC„) is greater than 2 milligrams and less than or equal to 20 milligrams per liter by volume when <br />inhaled continuously for one hour or less. EPA Category 111. <br />3. Moderately Toxic: The probable lethal dose of undiluted product to 50% of the test animals determined from <br />inhalation studies (LC„) is greater than 0.2 milligrams and less than or equal to 2 milligrams per liter by volume <br />when inhaled continuously for one hour or less. EPA Category II. <br />4. Highly Toxic:The probable lethal dose of undiluted product to 50% of the test animals determined from inhala- <br />tion studies (LC„) is less than or equal to 0.2 milligrams per liter of volume when inhaled continuously for one <br />hour or less. EPA Category 1. <br />