COMPLIANCE INFO_2019 - Laserfiche WebLink

Home Browse Search

"Your Safer Source for Science." Chemical Disposal Procedures 1339 Disposal Procedures FLINN [METHOD . 0 # 1 cl Organic Aad Halides and Slowly add a few-milliliters or grams of the acid halide or anhydride to Aad Anhydrides the container while constantly stirring. You can tell the decomposition reaction is occurring when the material begins to dissolve. The evolu- Products in this class readily react with water, amines, and alcohols. tion of gaseous carbon dioxide should also be evident. They are also generally corrosive and their vapors are lachrymators. Acid halides and acid anhydrides may be RCRA listed and/or cbarac- teristic wastes due to their reactivity or flammability. Leftover organic O acid derivatives remaining in an experiment may be hydrolyzed to If a noticeable temperature rise is observed, place the container in an water-soluble products of low toxicity that can be flushed down the ice-water bath. drain. The reactions are exothermic; immerse the reaction vessel in ice water to control the heat. Examples Adipoyl chloride and acetic anhydride 0 Materials Required Continue slow addition of the acid derivative while stirring until all the Large glass or polyethylene container Saturated solution of sodium carbonate (200 g Na2CO3/L) compound has been consumed. Stirring rod Hydrochloric acid, HCl, 3 M Pit paw pH paper Ice-water bath (optional) O Overview When a clear solution has Acid halides and acid anhydrides are reacitve derivatives of carboxylic been obtained, cool it to mom acids. These substances react with water to form the . original organic temperature and neutralize to ptlUr acid or its conjugate base in basic solution. Excess acid halide or acid pH 7 with 3 M hydrochloric anhydride remaining in a reaciton mixture may be. decomposed with acid saturated sodium carbonate solution. The acid anhydride or acid halide reacts with water, and the products of that reaction, which are acidic, F M immediately react with sodium carbonate to form a salt of the acid. Most carboxylic acid salts are innocuous and may be flushed down the drain. Gaseous carbon dioxide is also produced, also forms, which will produce a fizzing as the reaction proceeds. The reaction of acetic anhydride proceeds as follows: 0 (CMCO)zO + H2O -42CH3COOH Flush the neutral mixture down the drain with a 20-fold excess 2CH3COOH + Na2CO3 -+ 2NaCH3C00 + CO2 + MO of water. Note that one mole of sodium carbonate is required to fully neutral- ize one mole of the original acid halide or acid anhydride. To push the reaction to completion, a twofold molar excess of sodium carbonate is recommended. At 25 °C; a saturated sodium carbonate solution contains about 2 moles of sodium carbonate per liter of solution. Sodium hydroxide solution. (2 M) may he substituted for saturated S ` sodium carbonate in this procedure. Chers T0000 ru Both adipoyl chloride and sebacoyl chloride contain two chlorine Tea atoms per molecule. Use a fourfold molar excess of sodium carbonate solution to hydrolyze these compounds. F01111 Procedure iiaisChem 0 Perform this procedure in a fume hood. Wear chemical splash goggles, chemicals-resistant gloves, and a lab coat or chemical-resistant apron. • Please ... Read the Narratives Important narratives precede these specific chemical disposal methods ! Please read each narrative carefully ! Do not use these procedures if you are not comfortable with the chemistry. Do Place a saturated solution of sodium not use these procedures without fust consulting with your local carbonate in a large glass or plastic government regulatory officials. These procedures may not be container. 1 used in some jurisdictions. All procedures involve some hazards and risks. Once again . . . read the narratives that precede these ke and Wafer I "' specific chemical disposal methods.