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Preservabalance 19-Dec-05 CARCINOGENICITY : Disodium Octaborate , tetrahydrate is not listed as a carcinogen by IARC , NTP or OSHA . A Technical Report on Boric Acid issued by the National Toxicology Program reported no evidence of carcinogenicity . No mutagenic activity was reported in a battery of four mutagenic assays . REPRODUCTIVE/DEVELOPMENTAL EFFECTS : There is insufficient information on the potential for reproductive effects of borates in humans . Adverse testicular effects and infertility have been reported in laboratory animals . There have been limited animal studies which suggest decreased ovulation , fetotoxicity and developmental effects may occur at very high doses . Maternal toxicity was present in some studies . ACUTE TOXICITY DATA Eye Irritation Rabbits — Mildly Irritating Skin Irritation Rabbits - Slightly Irritating Acute Dermal Toxicity Rats - LD50 > 5000 mg/kg (No signs of gross toxicity , adverse pharmacologic effects or abnormal behavior. All animals survived and appeared active and healthy .) Acute Oral Toxicity Rats - LD50 = 2752 mg/kg (Toxic signs noted included ano-genital staining, diarrhea , reduced fecal volume and hypoactive and/or hunched posture . Effects were noted on the lungs , intestines and/or liver at the 5 ,000 mg/kg dose . ) Acute Inhalation Toxicity Rats - LC50 >5 . 06 mg/L/4 hour Dermal Sensitization Guinea Pigs — Not a Sensitizer 12. ECOLOGICAL INFORMATION Boron is naturally occurring in the environment . Disodium octaborate tetrahydrate is soluble in water and leachable through soil . Disodium octaborate tetrahydrate decomposes in the environment to natural borate . High concentrations of boron can be harmful to boron sensitive plants . Plants and trees can be exposed by root absorption to toxic levels of boron if water soluble borates contaminate water and soil . Care should be taken to avoid environmental contamination with this product. The following are acute ecotoxicity values for disodium octaborate tetrahydrate : Rainbow trout 24 - day LC50 = 88 mg Boron/L ; 36-day LC50 = 54 mg Boron/L Goldfish 3 - day LC50 = 71 mg Boron/L ; 7- day LC50 = 65 mg Boron/L Daphnia magna 24- hour EC50 = 242 mg Boron/L 13 DISPOSAL CONSIDERATIONS WASTE DISPOSAL : This substance , when discarded or disposed of, is not listed as a hazardous waste in Federal regulations . Chemical additions , processing or otherwise altering this material may make the waste management information presented in this MSDS incomplete, inaccurate or otherwise inappropriate . The disposal of this waste material must be conducted in compliance with all applicable Federal , state , and local regulations . 14. TRANSPORTATION REQUIREMENTS Disodium octaborate tetrahydrate is not regulated as a hazardous material for transportation by the US Department of Transportation , the Canadian Transportation of Dangerous Goods Regulations or international regulations . 15`. REGULATORY INFORMATION SARA TITLE III INFORMATION : Section 311 /312 (40 CFR 370 ) : Listed below are the hazard categories for the SUPERFUND Amendments and Reauthorization Act ( SARA) Immediate Hazard : _ Delayed Hazard : X Fire Hazard : _ Pressure Hazard : _ Reactivity Hazard : _ Section 313 (40 CFR 372 ) : This product does not contain toxic chemicals that are subject to the annual toxic chemical release reporting requirements of the SUPERFUND Amendments and Reauthorization Act ( SARA ) . Section 302 (40 CFR 355 ) : This product contains no chemicals listed as extremely hazardous chemicals under SUPERFUND Amendments and Reauthorization Act ( SARA) . Page 4 of 5