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D-LT PRIMER Section 11. Toxicological information Classification Prod uctlingredient name OSHA IARC NTP titanium dioxide - 2B - IARC has issued a notice that they will publish a monograph that lists titanium dioxide (TiO2) as possibly carcinogenic to humans (Group 213) by inhalation (based solely on animal data). Human epidemiology studies do not suggest an increased risk of cancer in humans for occupational exposure to titanium dioxide. According to the IARC summary on titanium dioxide, "No significant exposure to titanium dioxide is thought to occur during the use of products in which titanium dioxide is bound to other materials, such as paint.". Reproductive toxicity Not available. Teratogenicity Not available. Specific target organ toxicity (single exposurel Name Category Route of Target organs exposure titanium dioxide Category 3 Not applicable. Respiratory tract irritation SRecif" target or toxicity(repeated exposure) Not available. Aspiration hazard Not available. Information on the likely : Not available. routes of exposure Potential acute health effects Eye contact : No known significant effects or critical hazards. Inhalation : No known significant effects or critical hazards. Skin contact : No Known significant effects or critical hazards, Ingestion : No known significant effects or critical hazards, Symptoms related to the physical, chemical and toxicological characteristics Eye contact : No specific data. Inhalation No specific data. Skin contact No specific data. Ingestion ; No specific data. Delayed and immediate effects and also chronic effects from short and Ion term exposure Short term exposure Potential immediate Not available. effects Potential delayed effects Not available. Long term exposure Potential immediate Not available. effects Date of issue/Date of revision :11/20/2018 Date ofprevious issue :111912018 Version :1.24 7/11