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SYNS:
<br />ANKILOSTIN
<br />ANTISOL 1
<br />CARBON BICHLORIDE
<br />CARBON DICHLORIDE
<br />CZTEROCHLOROETYLEN (POL-
<br />ISH)
<br />DIDAKENE
<br />DOW-PER
<br />ENT 1.860
<br />ETHYLENE 1E1KACHLORIDE
<br />PEDAL-UN
<br />NCI-004580
<br />NEMA
<br />PERA WIN
<br />PERCHLOORETHYLEEN. PER
<br />(DUTCH)
<br />PERCHLOR
<br />PERCHLORAETHYLEN, PER (GER-
<br />MAN)
<br />PERCHLORETHYLENE
<br />PERCHLORETHYLENE. PER
<br />(FRENCH)
<br />PERCHLOROETHYLENE (ACGIH,
<br />DOT)
<br />PERCLENE
<br />PERCLOROETILENE (ITALIAN)
<br />PERCOSOLVE
<br />PERK
<br />PERKLONE
<br />PERSEC
<br />RCRA WASTE NUMBER U210
<br />TETLEN
<br />Et RACAP
<br />TETRACHLOORETHEEN (DUTCH)
<br />E 1 RACHLORAETHEN (GERMAN)
<br />TETRACHLOROETHENE
<br />TETFtACHLOROETHYLENE (DOT)
<br />E I RACLOROETENE (ITALIAN)
<br />TETRALENO
<br />1 EIRALEX
<br />1 I KAVEC
<br />TETROGUER
<br />it KOPIL
<br />TB0250 1,1,2,2-TETRACHLOROETh T LENE
<br /> 3190
<br />PROP: Liquid. D: 1.588 @ 20/4°, bp: 129-130°. Sol in
<br />water; misc in alc, ether.
<br />SYNS:
<br />NCI-052459
<br /> RCRA WASTE NUMBER U208
<br />TOXICITY DATA: CODEN:
<br />skn-rbt 500 mg/24H
<br /> AMPMAR 35,593,74
<br />eye-rbt 100 mg SEV
<br /> AMPMAR 35,593,74
<br />orl-mus TDLo:129 g/kg/2Y-I: NTPTR* NTP-TR-
<br />CAR
<br /> 237,82
<br />orl-mus TD:258 g/kg/2Y-1:CAR
<br /> NTPTR* NTP-TR-
<br />237,82
<br />IARC Cancer Review: Animal Limited Evidence IMEMDT
<br />41,87,86. NTP Carcinogenesis Bioassay (gavage); Clear
<br />Evidence: mouse NTPTR* NTP-TR-237,82; (gavage); No
<br />Evidence: rat NTPTR* NTP-TR-237,82. Reported in EPA
<br />TSCA Inventory.
<br />THR: An experimental carcinogen. A skin and severe eye
<br />irritant. Incompatible with dinitrogen tetraoxide; 2,4-dini-
<br />trophenyl disulfide; potassium; potassium hydroxide; nitro-
<br />gen tetroxide; sodium; sodium potassium alloy. When
<br />heated to decomposition it emits very toxic fumes of C1.
<br />For further information, see Vol. 4, No. 3 of DPIM Re-
<br />port.
<br />TBQ250 HR: 3
<br />1,1,2,2-TETRACHLOROETHYLENE
<br />CAS: 127-18-4 NIOSH: KX 3850000
<br />DOT: 1897
<br />mf: C2C14 mw: 165.82
<br />PROP: Colorless liquid; chloroform-like odor. Mp:
<br />—23.35°, bp: 121.20°,d: 1.6311 @ 15°/4°, vap press: 15.8
<br />mm @ 22°, vap d: 5.83.
<br />TOXICITY DATA: CODEN:
<br />skn-rbt 810 mg/24H SEV
<br /> JETOAS 9,171,76
<br />eye-rbt 162 mg MLD
<br /> JETOAS 9,171,76
<br />nuno-sat 50 pi/plate NIOSH* 5AUG77
<br />mma-sat 200 'IL/plate NIOSH* 5AUG77
<br />dns-hmn:lng 100 mg/L
<br /> NTIS** PB82-185075
<br />otr-rat:emb 97 p.mol/L
<br /> ITCSAF 14,290,78
<br />ihl-rat TCLo:1000 ppm/24H
<br /> APTOD9 19,A21,80
<br />(I4D pre/1-22D preg):TER
<br />ihl-rat TCLo:900 ppm/7H
<br /> TJADAB 19,41A,79
<br />(7-13D preg):REP
<br />ihl-mus TCLo:300 ppm/7H
<br /> TXAPA9 32,84,75
<br />(6-15D preg):TER
<br />orl-mus TDLo:195 g/kg/50W-I: NCITR* NCI-CG-TR-
<br />CAR
<br /> 13,77
<br />orl-mus TD :240 g/kg/62W-1: NCITR* NCI-CG-TR-
<br />CAR
<br /> 13,77
<br />ihl-hmn TCLo:96 ppm/7H: N1'1S** PB257-185
<br />PNS,EYE,CNS
<br />ihl-man TCLo:280 ppm/2H: AMIHBC 5,566,52
<br />EYE,CNS
<br />ihl-man TCLo:600 ppm/10M: AMIHBC 5,566,52
<br />EYE,CNS
<br />ihl-man LDLo:2857 mg/kg: MLDCAS 5,152,72
<br />CNS,PUL
<br />on-rat LD50:8850 mg/kg NPIRI* 1,96,74
<br />ihl-rat LCLo:4000 ppm/4H
<br /> JOCMA7 4,262,62
<br />orl-mus LD50:8100 mg/kg NTIS** PB257-185
<br />ihl-mus LC50:5200 ppm/4H
<br /> AP1'0A6 9,303,53
<br />ipr-mus LD50:4700 mg/kg NT1S** PB257-185
<br />on-dog LDLo:4000 mg/kg AJHYA2 9,430,29
<br />ipr-dog LD50:2100 mg/kg TXAPA9 10,119.67
<br />ivn-dog LDLo:85 mg/kg QJPPAL 7.205,34
<br />orl-cat LDLo:4000 mg/kg AJHYA2 9,430,29
<br />orl-rbt LDLo:5000 mg/kg AJHYA2 9,430,29
<br />scu-rbt LDLo:2200 mg/kg QJPPAL 7,205,34
<br />IARC Cancer Review: Animal Limited Evidence IMEMDT
<br />20,491,79. NCI Carcinogenesis Bioassay (gavage); Clear
<br />Evidence: mouse NCITR* NCI-CG-TR-13,77; (inhalation);
<br />Clear Evidence: mouse, rat NTPTR* NTP-TR-311,86; (ga-
<br />vage); Inadequate Studies: rat NCITR* NCI-CG-TR-13,77.
<br />Reported in EPA TSCA Inventory. EPA Genetic Toxicol-
<br />ogy Program. Community Right To Know List.
<br />OSHA PEL: TWA 100 ppm; CL 200 ppm; Pk 300pprn/
<br />5M/3H
<br />ACGIH TLV: TWA 50 ppm (skin); STEL 200 ppm
<br />DFG MAK: 50 ppm (345 mg/m3); BAT: blood 100 1.14/d1
<br />NIOSH REL: (Tetrachloroethylene) Minimize workplace
<br />exposure.
<br />DOT Classification: Poison B; Label: St. Andrews Cross;
<br />ORM-A; Label: None
<br />THR: Experimental poison by intravenous route. Moder-
<br />ately toxic to humans by inhalation with the following ef-
<br />fects: local anesthetic, conjunctiva irritation, general an-
<br />esthesia, hallucinations, distorted perceptions, coma and
<br />pulmonary changes. Moderately experimentally toxic by
<br />ingestion, inhalation, intraperitoneal and subcutaneous
<br />routes. An experimental carcinogen and teratogen. Experi-
<br />mental reproductive effects. Human mutagenic data. An
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