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PEL 25 ppm OSHA Specifically Regulated <br />Chemicals/Carcinogens <br />carcinogen OSHA specifically regulated <br />STEL 125 ppm OSHA Specifically Regulated <br />Chemicals/Carcinogens <br />carcinogen OSHA specifically regulated <br />PEL 25 ppm <br />87 mg/m3 <br />California permissible exposure <br />limits for chemical <br />contaminants (Title 8, Article <br />107) <br />STEL 125 ppm <br />435 mg/m3 <br />California permissible exposure <br />limits for chemical <br />contaminants (Title 8, Article <br />107) <br />Biolo ical occu ational exposure limits <br />Component CAS-No. Parameters Value Biological <br />specimen <br />Basis <br />Dichloromethane 75-09-2 Dichloromet <br />hane <br />0.3 mg/I Urine ACGIH - <br />Biological <br />Exposure Indices <br />(BEI) <br />Remarks End of shift (As soon as possible after exposure ceases) <br />Derived No Effect Level DNEL <br />Application Area Routes of <br />exposure <br />Health effect Value <br />Workers Inhalation Acute systemic effects 706 mg/m3 <br />Workers Inhalation Long-term systemic effects 353 mg/m3 <br />Workers Skin contact Long-term systemic effects 4750mg/kg BW/d <br />Consumers Ingestion Long-term systemic effects 0.06mg/kg BW/d <br />Consumers Inhalation Long-term systemic effects 88.3 mg/m3 <br />Consumers Skin contact Long-term systemic effects 2395mg/kg BW/d <br />Consumers Inhalation Acute systemic effects 353 mg/m3 <br />Predicted No Effect Concentration (PNEC ) <br /> <br />Value <br /> <br />Compartment <br /> <br />Soil 0.583 mg/kg <br />Sea water 0.194 mg/I <br />Fresh water 0.54 mg/I <br />Sea sediment 1.61 mg/kg <br />Fresh water sediment 4.47 mg/kg <br />Onsite sewage treatment plant 26 mg/I <br />Aquatic intermittent release 0.27 mg/I <br />8.2 Exposure controls <br />Appropriate engineering controls <br />Immediately change contaminated clothing. Apply preventive skin protection. Wash <br />hands and face after working with substance. <br />Personal protective equipment <br />Eye/face protection <br />Use equipment for eye protection tested and approved under appropriate <br />government standards such as NIOSH (US) or EN 166(EU). Safety glasses <br />Sigma-Aldrich - 270997 <br />Page 5 of 12 <br />The life science business of Merck KGaA, Darmstadt, Germany <br /> MilliPORe <br />operates as MilliporeSigma in the US and Canada SiGNia