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`:XTOXNI--T PIP - FENAMIPHOS <br />EXTOXNET <br />Extension Toxicology Network <br />Pesticide Information Profiles <br />.tp://acc.orst.edu/cgi-bin/mis/01 /pips/Icnami ph. ht <br />A Pesticide Information Project of Cooperative Extension Offices of Cornell University, Oregon State <br />University, the University of Idaho, and the University of California at Davis and the Institute for <br />Environmental Toxicology, Michigan State University. Major support and funding was provided by the <br />USDA/Extension Service/National Agricultural Pesticide Impact Assessment Program. <br />EXTOXNET primary files maintained and archived at Oregon State University <br />Revised June 1996 <br />Fenamiphos <br />Trade and Other Names: Trade names for products containing fenamiphos include Bay 68138, <br />Nemacur and Phenamiphos. It may also be found in formulations with other pesticides such as <br />isofenphos, carbofuran and disulfoton. <br />Regulatory Status: Fenamiphos is an highly toxic compound in EPA toxicity class I. It is a <br />Restricted Use Pesticide (RUP). RUPs may be purchased and applied only by a certified applicator. <br />Labels for products containing fenamiphos must carry the Signal Word DANGER. <br />Chemical Class: organophosphate <br />Introduction: Fenamiphos is an organophosphate nematicide used to control a wide variety of <br />nematode (roundworm) pests. Nematodes can live as parasites on the outside or the inside of a plant. <br />They may be free living or associated with cyst and root -knot formations in plants. Fenamiphos is used <br />on a variety of plants including tobacco, turf, bananas, pineapples, citrus and other fruit vines, some <br />vegetables, and grains. The compound is absorbed by roots and is then translocated throughout the plant. <br />Fenamiphos, as is typical of other organophosphates, blocks the enzyme acetylcholinesterase in the <br />target pest. The pesticide also has secondary activity against other invertebrates such as sucking insects <br />and spider mites. It is available in emulsifiable concentrate, granular, or emulsion formulations. <br />Formulation: It is available in emulsifiable concentrate, granular, or emulsion formulations. <br />Toxicological Effects: <br />Acute toxicity: Fenamiphos is highly toxic via the oral route, with reported LD50 values of 2 to 19 <br />mg/kg in the rat and 56 to 100 mg/kg in guinea pigs. It is also highly toxic to dogs and rabbits <br />I ora 5/12,'00 2:02 Pit <br />