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Lub of Version : Revision Date : 07/ 18/2023 ow + + Naphthalene Naphthalene has caused mutagenic effects in in vitro studies with metabolic activation , however, in vivo studies do not show evidence of germ cell mutagenicity. Toluene In vitro and in vivo genetic toxicity studies were negative . Results of tests in workers exposed to higher concentrations of toluene have shown that this material can cause irreversible changes in the genetic material ( DNA) of a cell . The human health consequences of these changes is not fully understood . Reproductive toxicity : Xylene Not Classified based on available data . Based on available data this product is not expected to be classified a reproductive hazard . Xylene is fetotoxic in rats and rabbits in the absence of maternal toxicity . + + Ethyl benzene Not Classified based on available data . Based on available data this product is not expected to be classified a reproductive hazard . 2-Ethylhexanol No evidence of adverse effects were found in a developmental toxicity study of 2-ethylhexanol in rats . Doses up to 3 ml/kg applied to the skin during the most critical part of the gestation period produced evidence of toxicity to mothers , but no evidence of injury in the developing offspring . In a previous study, birth defects were observed by oral administration , an unlikely route of exposure in the workplace. Hydroxyalkyl carboxylic ester Based on available data this product is not expected to be classified a reproductive hazard . Toluene Prolonged and repeated exposure of pregnant animals to toluene by inhalation has been reported to cause adverse fetal developmental effects . Specific Target Organ Toxicity - Repeated Exposure : Xylene Xylene has been found to cause cardiac , liver and kidney effects , anemia and eye damage in laboratory animals . Prolonged and repeated inhalation of hydrocarbon solvents such as xylene can cause chronic neurological disturbances . Chronic exposure to xylene has been shown to cause hearing loss in experimental animals . Unknown : Target Organ (s ) : Central nervous system . , Hearing ++ Ethyl benzene Target Organ (s ) : hearing , Kidney, Liver Petroleum naphtha Repeated overexposure to petroleum naphtha can cause nervous system damage . 2-Ethylhexanol Repeated overexposure may result in liver and kidney damage . A 14-day dermal toxicity study of 2-ethylhexanol in rats showed blood effects , decreased spleen weight and decreased triglycerides . Unknown : Target Organ (s) : Blood , Liver, Spleen . , Kidney SDS US - ULTRAZOL® GA9058 12/19