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Sheet Steel
<br /> 11 , TOXICOLOGICAL INFORMATION
<br /> The primary component of this product is iron , Long -term exposure to iron dusts or fumes can result in a
<br /> condition called siderosis which is considered to be a benign pneumoconiosis . Symptoms may include
<br /> chronic bronchitis , emphysema , and shortness of breath upon exertion , Penetration of iron particles in the
<br /> skin or eye may cause an exogenous or ocular siderosis which may be characterized by a red -brown
<br /> pigmentation of the affected area . Ingestion overexposures to iron may affect the gastrointestinal , nervous ,
<br /> and hematopoietic system and the liver, Iron and steel founding , but not iron or iron oxide , has been listed
<br /> as carcinogenic (Group 1 ) by IARC .
<br /> When this product is welded , fumes are generated . Welding fumes may be different in composition from the
<br /> original welding product , with the chief component being ordinary oxides of the metal being welded , Chronic
<br /> health effects (including cancer) have been associated with the fumes and dusts of individual component
<br /> metals (see above) , and welding fumes as a general category have been listed by IARC as a carcinogen
<br /> (Group 26) . There is also limited evidence that welding fumes may cause adverse reproductive and fetal
<br /> effects . Evidence is stronger where welding materials contain known reproductive toxins , e .g . , lead which
<br /> may be present in the coating material of this product ,
<br /> Breathing fumes or dusts of this product may result in metal fume fever, which is an illness produced by
<br /> inhaling metal oxides , These oxides are produced by heating various metals including cadmium , zinc ,
<br /> magnesium , copper, antimony, nickel , cobalt , manganese , tin , lead , beryllium , silver, chromium , aluminum ,
<br /> selenium , iron , and arsenic. The most common agents involved are zinc and copper .
<br /> This product may contain small amounts of manganese . Prolonged exposure to manganese dusts or fumes
<br /> is associated with " manganism " , a Parkinson-like syndrome characterized by a variety of neurological
<br /> symptoms including muscle spasms , gait disturbances , tremors , and psychoses .
<br /> This product may contain small amounts of cadmium . Primary target organs for cadmium overexposure are
<br /> the lung and the kidney. Because of its cumulative nature , chronic cadmium poisoning can cause serious
<br /> disease which takes many years to develop and may continue to progress despite cessation of exposure ,
<br /> Progression of the disease may not reflect current exposure conditions . It is also capable of causing a painful
<br /> osteomalacia called " Itakitai" in postmenopausal women , and has caused developmental effects and/or
<br /> reproductive effects in male and female animals . Cadmium is a listed carcinogen by NTP , OSHA , and IARC
<br /> (Group 1 ) .
<br /> This product may contain small amounts of chromium . Prolonged and repeated overexposure to chromium
<br /> dusts or fumes may cause skin ulcers , nasal irritation and ulceration , kidney damage and cancer of the
<br /> respiratory system . Chromium is skin sensitizer. Cancer is generally attributed to the hexavalent (+ 6) form
<br /> of chromium which is listed as a carcinogen by NTP and IARC (Group 1 ) .
<br /> This product may contain small amounts of nickel . Prolonged and repeated contact with nickel may cause
<br /> sensitization dermatitis . Inhalation of nickel compounds has caused lung damage as well as sinus , nasal and
<br /> lung cancer in laboratory animals . Nickel is a listed carcinogen by NTP and IARC (Group 1 ) ,
<br /> This product may contain small amounts of vanadium . Adverse effects from dermal , inhalation or parenteral
<br /> exposure to various vanadium compounds have been reported . The major target for vanadium pentoxide
<br /> toxicity is the respiratory tract . Fumes or dust can cause severe eye and respiratory irritation , and systemic
<br /> effects . Chronic bronchitis , green tongue , conjunctivitis , pharyngitis , rhinitis , rales , chronic productive cough ,
<br /> and tightness of the chest have been reported following overexposure . Allergic reactions resulting from skin
<br /> and inhalation exposures have also been reported . A statistical association between vanadium air levels and
<br /> lung cancer has been suggested , but vanadium currently is not regarded as a human carcinogen .
<br /> This product may contain small amounts of lead . Lead can accumulate in the body . Consequently , exposure
<br /> to fumes or dust may produce signs of polyneuritis , diminished vision and peripheral neuropathy, such as
<br /> tingling and loss of feeling in fingers , arms and legs. Lead is a known reproductive and developmental toxin .
<br /> it is also associated with central nervous system disorders , anemia , kidney dysfunction and neurobehavioral
<br /> abnormalities . The brain is a major target organ for lead exposure. Elemental lead is listed as an IARC 2B
<br /> carcinogen ,
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