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MATERIAL SAFETY DATA SHEET 200001455/F/USA - Q-0032.620I Approval Date: 09/26/1997 Print Date: 09/27/1997 Page 10 stomach upset, hives, faintness, weakness and diarrhea. Acute Toxicity Data: Part B: Data for hydroxylamine sulfate Oral LD-50 (rat) : 100-200 mg/kg Dermal LD-50: >1 .0 g/kg Skin irritation: moderate Skin sensitization: strong Eye irritation: slight Dermal study (rat) : 0.01-05 g/kg 24 hours (target organ effects: red blood cell) Dermal study: 0.01 g/kg 24 hours (target organ effects: red blood cell) Part C: Data for 4-(N-ethyl-N-2-hydroxyethyl)-2-methylphenylenediamine sulfate Oral LD-50 (male rat) : 25-50 mg/kg (target organ effects: kidney) Oral LD-50 (female rat) : 30 mg/kg (target organ effects: kidney) Oral LD-50 (mouse) : 141 mg/kg (target organ effects: kidney) Dermal LD-50: >2000 mg/kg Skin irritation: moderate Repeated skin application: moderate irritation Skin sensitization (human) : positive Eye irritation (unwashed eyes) : moderate Eye irritation (washed eyes) : slight Inhalation study (164 mg/m3, 6 hours, rat) :, 0/10 died Definitions for the following section(s) : LOEL = lowest-observed-effect level , LOAEL = lowest-observed-adverse-effect, NOAEL = no observed-adverse-effect level, NOEL = no-observed-effect level . Subchronic Toxicity Data: Oral study (4 weeks , female rat) : NOEL = 1 mg/kg/day, LOEL = 10 mg/kg/day (target organ effects: kidney) Oral study (4 weeks , male rat) : NOEL = 10 mg/kg/day, LOEL = > 10 mg/kg/day (target organ effects: kidney) Oral study (90 days, rat) : NOEL = 1 mg/kg /day , LOEL = 5 mg/kg/day (target organ effects: kidney) Dermal absorption rate (rat, in vitro) : 93. 7 microgram(s)/cm2/hour ------------------------------------------------------------------------------ 12. ECOLOGICAL INFORMATION