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siAll <br /> :"� _..why.,.. _,�.. a aw:..n� 'n,,,•....�,i ��„_s,�6:..= -MS;,.; �� i,�+ :w. ...�'-�S �. `» ;a. tG �4 1;�,,�.:4 ire <br /> s_ <br /> To]uene <br /> INSDS-1019 <br /> Page 3 <br /> Mutagenicity <br /> RG: C Monographs have not reported mutagenic effects. <br /> RTzCS: Positive mutagenic reponses were observed in bacteria and in <br /> rat cel Is <br /> Terata eni ci ty <br /> onographs have not reported teratogenic effects. <br /> RTAS: Developmental abnormalities in the musculoskeletal system of <br /> rats and in the craniofacial region of mice have been observed. <br /> Reproductive Effects <br /> IARC: AMonographs have not reported reproductive effects. <br /> =S: Fetotoxicity was observed in rats and mice, and fetal death was <br /> observed in mice. <br /> SECTION V. CHRONIC TOXICITY <br /> Possible dermatitis, drying, and cracking of the skin may result from <br /> repeated or prolonged skin contact. Liver and kidney injury may <br /> occur after prolonged exposure. <br /> SECTION VI. PHYSICAL DATA <br /> Molecular weight: 92.1 <br /> 80—ITing Point at 760 mm Hg): 110.5 C (231°r) <br /> e tin oint at 760 mm -95'C (-139'F) <br /> Vapor Pressure mm Hg at 20°C (680F)]: 22 <br /> Vapor Uensity (Ait-_1): <br /> Specific Gravity water=l): 0.866 <br /> Percent Volatile 8y Volume: 100 <br /> Evaporation Rate (butyl acetate =1) : 2.24 <br /> Solubility inWater: I �g/1009 f water, at 20% (68°F) <br /> Solvent Solubility: Soluble in acetone, miscible in absolute alcohol, <br /> ether, and chroroform. <br /> Appearance and Odor: Water white liquid with a characteristic aromatic <br /> odor, w1hose recognition threshold (unfatigued) is 2-5 ppm (100 <br /> percent of test panel ). Odor detection is unsatisfactory for safety <br /> because of fatigue. <br /> SECTION VII. FIRE AND EXPLOSION HAZARD DATA <br /> ' Flash Point (Method Used). 4°C (40°F) (closed cup) <br /> xtin gu i sh er a ia: CV2, dry chemical , foam, water fog. <br /> Lower Upper <br /> Flammable Limits in Air, percent by vol .o .2 . <br /> Auto ignition emperature:���� F) <br /> NFPA Fire Hazard: <br /> Special Fire Fighting Procedures: Self-contained breathing apparatus <br /> ;., <br /> and eye protection souT..d ee worn. <br /> Unusual Fire and Explosion hazards: At room temperature toluene emits <br /> vapors thar, can torm tjammaMe mixtures with air. When exposed to <br /> heat and flame it is a dangerous fire hazard and a moderate explosion <br /> ENOR Ogic dATA <br />