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Peter MacNichotl. <br /> February 2,:2009 <br /> DD.1C site. <br /> Page 3 <br /> the ingestion dose equation whereas an age-adjusted dermal factor was not. In evaluating the <br /> residential scenario, a skin surface area of 6600 cmc for a child resident should be included in <br /> the dermal dose equation or in deriving an age-adjusteddermal'factor. <br /> CONCLUSIONS <br /> The discussion on the human health risk assessment contains inaccuracies that are identified in <br /> the preceding specific comments. An adequate understanding of each component in a health <br /> risk assessment will resolve these deficiencies. HERD concurs that all the risk estimates <br /> exceeded the point of departure of 1 E-06 under both residential and industrial scenarios. <br /> HERD does not agree with the approach of developing risk-based concentrations for the <br /> residential scenario based solely on groundwater ingestion. The forward evaluation assumed <br /> complete exposures via ingestion and dermal contact. Considering that the primary contributor <br /> to the cumulative risk is the dermal pathway, elimination of this pathway in developing health <br /> protective concentrations in groundwater is invalid. As noted in specific comment #9, the <br /> evaluation of the hypothetical resident's exposures via domestic use of groundwater should <br /> Include both adult and child receptors. Therefore, inclusion of the dermal pathway could <br /> potentially result in risk-based concentrations lower than the range of 0.004 to 0.4 ug/L for the <br /> residential scenario, <br /> The selected alternative is the implementation of land-use controls on groundwater use and <br /> installation of water production wells. HERD defiers to the risk managers for concurrence on the <br /> proposed alternative. However, HERD recommends that the human health risk assessment be <br /> revised to address the deficiencies. <br /> Reviewed by ,Michael Jlade, Ph.D; DABT <br /> i� <br /> Senior Toxicologist <br /> t <br />