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:X'1 gXNE 1 P11'-ME1I11DATHION f "j/ace.orst.edu/cgi-bin/orfs/0I/pips/methidat.htm"4= <br /> ' EXTOXNET <br /> Extension Toxicology Network <br /> Pesticide Information Profiles <br /> A Pesticide Information Project of Cooperative Extension Offices of Cornell University, Oregon State <br /> University, the University of Idaho, and the University of California at Davis and the Institute for <br /> Environmental Toxicology, Michigan State University. Major support and funding was provided by the <br /> USDA/Extension Service/National Agricultural Pesticide Impact Assessment Program. <br /> EXTOXNET primary files maintained and archived at Oregon State University <br /> f <br /> Revised June 1996 <br /> t <br /> C <br /> Methidathion <br /> kTrade and Other Names: Trade names for products containing methidathion include Somonic, <br /> Somonil, Supracide, Suprathion and Ultracide. The compound may be found in formulations with <br /> many other pesticides. <br /> Regulatory Status: Methidathion is an highly toxic compound in EPA toxicity class I. Labels for <br /> I, products containing it must bear the Signal Word DANGER. Methidathion is a Restricted Use Pesticide <br /> [ (RUP), except for use in nurseries, and on safflower and sunflowers. <br /> Chemical Class: organophosphate <br /> Introduction: Methidathion is a non-systemic organophosphorous insecticide and acaricide with <br /> stomach and contact action. The compound is used to control a variety of insects and mites in many <br /> { crops such as fruits, vegetables, tobacco, alfalfa, and sunflowers, and also in greenhouses and on rose 1 <br /> ,4 cultures. It is especially useful against scale insects. it works by inhibiting certain enzyme actions in the <br /> target pests. It is available in emulsifiable concentrate, wettable powder, and ultra-low volume (ULV) <br /> liquid. <br /> Formulation: It is available in emulsifiable concentrate, wettable powder, and ultra-low volume <br /> (ULV) liquid formulations. <br /> l <br /> Toxicological Effects: <br /> • Acute toxicity: Methidathion is highly toxic via the oral route, with reported acute oral LD50 <br /> values of 25 to 54 mg/kg in the rat, and 18 to 25 mg/kg in the mouse [2,131. Other reported oral ] <br /> LD50 values include 25 mg/kg in guinea pigs, 80 mg/kg in rabbits, and 200 mg/kg in dogs [2]. It is <br /> highly toxic via the dermal route as well, with reported dermal LD50 values of 85 to 94 mg/kg in <br /> fI oN 1/26;00 8:16 AM <br />