SU0007436 SSCRPT - Laserfiche WebLink

Home Browse Search

3XTOXNET PIP - METHIDATHION Page 1 o EXTOXNET Extension Toxicology Network Pesticide Information Profiles k Pesticide Information Project of Cooperative Extension Offices of Cornell University, Oregon State University, the Jniversity of Idaho, and the University of California at Davis and the Institute for Environmental Toxicology,Michigan State University. Major support and funding was provided by the USDA/Extension Service/National Agricultural 3esticide Impact Assessment Program. ?XTOXNET primary files maintained and archived at Oregon State University 2evised June 1996 Methidathion grade and Other Names: Trade names for products containing methidathion include Somonic, Somonil, iupracide, Suprathion and Ultracide. The compound may be found in formulations with many other pesticides. lemic ulatory Status: Methidathion is an highly toxic compound in EPA toxicity class I. Labels for products :ontaining it must bear the Signal Word DANGER. Methidathion is a Restricted Use Pesticide (RUP), except for use in iurseries, and on safflower and sunflowers. :hemical Class: organophosphate Introduction: Methidathion is a non-systemic organophosphorous insecticide and acaricide with stomach and contac fiction. The compound is used to control a variety of insects and mites in many crops such as fruits,vegetables, tobacco, dfalfa, and sunflowers, and also in greenhouses and on rose cultures. It is especially useful against scale insects. It work )y inhibiting certain enzyme actions in the target pests. It is available in emulsifiable concentrate,wettable powder, and iltra-low volume (ULV) liquid. Formulation: It is available in emulsifiable concentrate, wettable powder, and ultra-low volume (ULV) liquid ormulations. toxicological Effects: . Acute toxicity: Methidathion is highly toxic via the oral route, with reported acute oral LD50 values of 25 to 54 mg/kg in the rat, and 18 to 25 mg/kg in the mouse [2,13]. Other reported oral LD50 values include 25 mg/kg in guinea pigs, 80 mg/kg in rabbits, and 200 mg/kg in dogs [2]. It is highly toxic via the dermal route as well, with reported dermal LD50 values of 85 to 94 mg/kg in the rat [2]. Methidathion is only a mild skin irritant and is nonirritating to the eyes (in rabbits). Via the inhalation route, it may be slightly toxic, with a reported 4-hour inhalation LC50 of 3.6 mg/L in rats [13]. Effects due to acute methidathion exposures are similar to those caused I other organophosphate pesticides, and may include nausea, vomiting, cramps, diarrhea, salivation, headache, ittp://extoxnet.orst.edu/pips/methidat.htm 7/2/20