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EXTOXNET PIP-PERMET "UN Page 1 of 3
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<br /> `, EXTOXNET
<br /> Extension Toxicology Network
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<br /> Pesticide Information Profiles
<br /> A Pesticide Information Project of Cooperative Extension Offices of Cornell University,Oregon State University,the
<br /> #Mn University of Idaho,and the University of California at Davis and the Institute for Environmental Toxicology,Michigan
<br /> State University.Major support and funding was provided by the USDA/Extension Service/National Agricultural Pesticide
<br /> Impact Assessment Program.
<br /> EXTOXNET primary files maintained and archived at Oregon State University
<br /> Revised June 1996
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<br /> Permethrin
<br /> Trade and Other Names:Trade names include Ambush,BW-21-Z,Cellutec,Dragnet,Ectiban,Eksmin,Exmin,FMC
<br /> 33297,Indothrin,Kafil,Kestrel,NRDC 143,Pounce,PP 557,Pramex,Qamlin,and Torpedo.
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<br /> Regulatory Status:Permethrin is a moderately to practically non-toxic pesticide in EPA toxicity class II or III,
<br /> depending on the formulation.Formulations are placed in class II due to their potential to cause eye and skin irritation.
<br /> Products containing permethrin must bear the Signal Word WARNING or CAUTION,depending on the toxicity of the
<br /> particular formulation.All products for agricultural uses(except livestock and premises uses)are Restricted Use Pesticides
<br /> (RUPs)because of their possible adverse effects on aquatic organisms.Restricted Use Pesticides may be purchased and used
<br /> only by certified applicators.
<br /> `. Chemical Class:pyrethroid
<br /> Introduction:Permethrin is a broad spectrum synthetic pyrethroid insecticide,used against a variety of pests,on nut,
<br /> 6M fruit,vegetable,cotton,ornamental,mushroom,potato,and cereal crops.It is used in greenhouses,home gardens,and for
<br /> termite control.It also controls animal ectoparasites,biting flies,and cockroaches.It may cause a mite buildup by reducing
<br /> mite predator populations.Permethrin is available in dusts,emulsifiable concentrates,smokes,ULV(ultra-low volume),and
<br /> wettable powder formulations.
<br /> Formulation:Permethrin is available in dusts,emulsifiable concentrates,smokes,ULV(ultra-low volume),and wettable
<br /> powder formulations.
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<br /> Toxicological Effects:
<br /> L . Acute toxicity:Permethrin is moderately to practically non-toxic via the oral route,with a reported LD50 for
<br /> technical permethrin in rats of 430 to 4000 mg/kg[12].Via the dermal route,it is slightly toxic,with a reported
<br /> dermal LD50 in rats of over 4000 mg/kg,and in rabbits of greater 2000 mg/kg[12,2].Permethrin caused mild
<br /> irritation of both the intact and abraded skin of rabbits.It also caused conjunctivitis when it was applied to the eyes
<br /> �.. [9].The 4-hour inhalation LC50 for rats was greater than 23.5 mg/L,indicating practically no inhalation toxicity.The
<br /> toxicity of permethrin is dependent on the ratio of the isomers present;the cis-isomer being more toxic[12].
<br /> Chronic toxicity:No adverse effects were observed in dogs fed permethrin at doses of 5 mg/kg/day for 90 days[15].
<br /> Rats fed 150 mg/kg/day for 6 months showed a slight increase in liver weights[9].Very low levels of permethrin in
<br /> the diet of chickens(0.1 ppm for 3 to 6 weeks after hatching)have been reported to suppress immune system activity
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<br /> http://extoxnet.orst.edu/pips/permethr.htm 9/26/2004
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