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Product Name:PRINT CARTRIDGE BLACK MP C3502 Number: <br /> Date Prepared 22/1 20111 Date Modified:05/07/2012 Date D:03108I2012841735 R,C®H <br /> Sectionl1 :Toxicological Information N ® <br /> Acute Toxicity inERM <br /> Acute Oral Toxicity(1-050): <br /> 5000 or over [mg/kgl (Rat) <br /> Acute Dermal Toxicity : OCT 15 2014 <br /> Not available <br /> Acute Inhalation Toxicity <br /> Not applicable (Based on other Ricoh products test results of similar ingredients, <br /> NVIRONMENTAL HEALTH <br /> Loral effects <br /> Acute Skin Irritation(P11): DEPARTMENT <br /> 1.0 or below (Rabbit)(Based on other Ricoh products test results of similar ingredients.) <br /> Acute Eye Irritation: <br /> Non-irritant(Rabbit)(Based on other Ricoh products test results of similar ingredients.) <br /> Sensitization <br /> Acute Allergenic Effects: <br /> Non-skinsensitive (Mouse)(Based on other Ricoh products test results of similar ingredients.) <br /> Specific Effects <br /> Carcinogenicity <br /> Carbon black and titanium dioxide contained in this product are classified to Group 2B of IARC as the <br /> result of inhalation test in use of rat. <br /> But oral/skin test does not show carcinogenicity. <br /> The toner containing carbon black did not show carcinogenicity in chronic inhalation exposure test in <br /> use of rat. <br /> In the animal experiment with very high concentration of fitanium dioxide(excessive burden of rays <br /> lungs clearance mechanism(overload phenomenon)),the rat alone showed lung tumor. Under a <br /> normal use practice,the concentration should be far lower than the above;and it is assumed that <br /> there is no such use. <br /> Also,relation between respiratory disease and work exposure of titanium dioxide is not observed with <br /> epidemiological survey. <br /> Mutagenicity : Negative(Ames test) <br /> Reproduction Toxicity : Does not contain substances listed as hazardous to reproductive health. <br /> Teratogenic : Not available. <br /> Section12: Ecological Information <br /> Mobility : No data are available on the adverse effect one environment. <br /> Persistence/Degradabilit : Not available <br /> y <br /> Bioamumulation : Not available <br /> Ecotoxicity <br /> Acute Toxicity for Fish(LC50) : Not classified as toxic(EU Directive 1999/45/EC)mg/1/96hr <br /> Acute Toxicity for Daphnia Not classified as toxic(EU Directive 1999/45/EC)mgn/48hr <br /> (EC50) <br /> Algae Inhibition Test(IC50) Not classified as toxic(EU Directive 1999/45/EC)mg/I/72hr <br /> —s— (ANSI] <br />