ARCHIVED REPORTS_DR OM AGREEMENT 2017 JANUARY

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Page 2 ALDRIN and DIELDRIN CAS # 309-00-2 and 60-57-1 ToxFAQs111 We do not know whether aldrin or dieldrin affect Is there a medical test to show whether I've been reproduction in humans. exposed to aldrin and dieldrin? There are laboratory tests that can measure aldrin and How likely are aldrin and dieldrin to cause dieldrin in your blood, urine, and body tissues. Because cancer? aldrin changes to dieldrin fairly quickly in the body, the test There is no conclusive evidence that aldrin or dieldrin cause has to be done shortly after you are exposed to aldrin. Since cancer in humans. Aldrin and dieldrin have been shown to dieldrin can stay in the body for months, measurements of cause liver cancer in mice. The International Agency for dieldrin can be made much longer after exposure to either Research on Cancer (IARC) has determined that aldrin and aldrin or dieldrin. The tests cannot tell you whether harmful dieldrin are not classifiable as to human carcinogenicity. The health effects will occur. These tests are not routinely EPA has determined that aldrin and dieldrin are probable available at the doctor's office because they require special human carcinogens. equipment. How can aldrin and dieldrin affect children? Has the federal government made Children can be exposed to aldrin and dieldrin in the same recommendations to protect human health? way as adults. There are no known unique exposure The EPA limits the amount of aldrin and dieldrin that may be pathways for children. Children who swallowed amounts of present in drinking water to 0.001 and 0.002 milligrams per aldrin or dieldrin much larger than those found in the liter (mg/L) of water, respectively, for protection against environment suffered convulsions and some died, as health effects other than cancer. The EPA has determined occurred in adults. However, we do not know whether that a concentration of aldrin and dieldrin of 0.0002 mg/L in children are more susceptible than adults to the effects of drinking water limits the lifetime risk of developing cancer aldrin or dieldrin. from exposure to each compound to 1 in 10,000. We do not know whether aldrin or dieldrin cause birth The Occupational Safety and Health Administration (OSHA) defects in humans. Pregnant animals that ingested aldrin or sets a maximum average of 0.25 milligrams of aldrin and dieldrin had some babies with low birth weight and some dieldrin per cubic meter of air (0.25 mg/m3) in the workplace with alterations in the skeleton. Dieldrin has been found in during an 8-hour shift, 40 hour week. The National Institute human breast milk, therefore, it can be passed to suckling for Occupational Safety and Health (NIOSH) also infants. recommends a limit of 0.25 mg/m3 for both compounds for up to a 10-hour work day, 40-hour week. How can families reduce the risk of exposure to aldrin and dieldrin? The Food and Drug Administration (FDA) regulates the ❑ Since aldrin and dieldrin are no longer produced or used, residues of aldrin and dieldrin in raw foods. The allowable exposure to these compounds will occur only from past range is from 0 to 0.1 ppm, depending on the type of food usage. product. ❑ Because aldrin and dieldrin were applied to the basement of some homes for termite protection, before buying a home References families should investigate what, if any, pesticides have been Agency for Toxic Substances and Disease Registry used within the home. (ATSDR). 2002. Toxicological Profile for Aldrin/Dieldrin (Update). Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service. Where can I get more information? For more information,contact the Agency for Toxic Substances and Disease Registry,Division of Toxicology, 1600 Clifton Road NE,Mailstop F-32,Atlanta,GA 30333.Phone: 1-888-422- 8737,FAX: 770-488-4178. ToxFAQs Internet address via WWW is http://www.atsdr.cdc.gov/toxfaq.html. ATSDR can tell you where to find occupational and environmental health clinics. Their specialists can recognize, evaluate, and treat illnesses resulting from exposure to hazardous substances. You can also contact your community or state health or environmental quality department if you have any more questions or concerns.