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diseases in humans ranging from aplastic anemia to leukemia (a form of cancer) All of these diseases can be fatal In some individuals, benzene exposure can sensitize cardiac tissue to epinephrine which may precipitate fatal ventricular fibrillation REPRODUCTIVE/DEVELOPMENTAL TOXICITY No birth defects have been shown to occur in pregnant laboratory animals exposed to doses not toxic to the mother However, some evidence of fetal toxicity such as delayed physical development has been seen at such levels The available information on the effects of benzene on human pregnancies is inadequate but it has been established that benzene can cross the human placenta OCCUPATIONAL The OSHA Benzene Standard (29 CFR 1910 1028)contains detailed requirements for training, exposure monitoring, respiratory protection and medical surveillance triggered by the exposure level Refer to the OSHA Standard before using this product SECTION 12 ECOLOGICAL INFORMATION ECOTOXICITY This material is expected to be toxic to aquatic organisms The 96 hour(s) LC50 for fathead minnow( Pimephales promelas) is 15 59 mg/i This information is based on test data from the component BENZENE ** The 24 hour(s) EC50 for water flea ( Daphnia magna) is 240 mg/I This information is based on test data from the component BENZENE** The 8 day(s) EC50 for green algae ( Selenastrum capncomutum ) is 41 mg/I This information is based on test data from the component BENZENE ** The 96 hour(s) LC50 for rainbow trout( Oncorhynchus mykiss) is 5 3-9 1 mg/I This information is based on test data from the component BENZENE ** ENVIRONMENTAL FATE Biodegradability This material is volatile and is expected to partition to air This material is expected to biodegrade under certain environmental conditions SECTION 13 DISPOSAL CONSIDERATIONS Use material for its intended purpose or recycle if possible This material, if it must be discarded, may meet the criteria of a hazardous waste as defined by US EPA under RCRA(40 CFR 261)or other State and local regulations Measurement of certain physical properties and analysis for regulated components may be necessary to make a correct determination If this material is classified as a hazardous waste, federal law requires disposal at a licensed hazardous waste disposal facility SECTION 14 TRANSPORT INFORMATION The description shown may not apply to all shipping situations Consult appropriate Dangerous Goods Regulations, for additional description requirements (e g , technical name)and mode-specific or quantity- specific shipping requirements Shipping Descriptions per regulatory authority US DOT BENZENE, 3, UN1114, II, RO (BENZENE) ICAO 1 IATA i BENZENE, 3, UN1114, II Revision Number 1 of BENZENE Revision Date 09/04/2003 MSDS GPG00091