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<br /> 121
<br /> 'age 3
<br /> . SECTION IV. LONG-TZRM ORGA:1I::4 THREAT POTVITIAL
<br /> Carcinoaenicit'
<br /> 1.: !ARC. Limited evidence of carcinogenic effect., In animals, Suf`icient
<br /> ` evsaence of carcinogenic affec°s In humans.
<br /> NTP/Nr,I: NTP/NIC' has reportadycarcinogenic affects,
<br /> u�AG has reported car:inogenic effects.
<br /> SCS: Carcinogenic by RT--Cs criteria based on cases of leakemia in
<br /> humans and rats. Carcinogenic by ,RTECs criteria in mice.
<br /> t4u:aaen_ s icity
<br /> Not mutagenic in bar.-0.'
<br /> yeast, insects, or mouse lymphoma
<br /> L ce'�s. Chromosomal anomalies in humans, rats, and mice were observed. l
<br /> ® RECS: Positive mutagenic responses in bacteria, mice, rats and
<br /> raooits were observed. ONA damage and chromosomal breaks ).i humans
<br /> ' l were observed.
<br /> Teratogenicity
<br /> —RRG. ail -abnormalities, Elect palate, and absenca of the lower e'
<br /> aw
<br /> ..! were defects observed in ;nice. Brain and skeletal defects in rats '-mere
<br /> observed, Other studies did not show teratogenic effects.
<br /> RTECs:. Abnormalities t ' the musculoskeletal Sys tam and other effects
<br /> on the newborn were obse-ved in rats and mice,
<br /> Reoroductive Effects
<br /> 1 : Ait&atioF of estrus cycles in rats was observed. Increased
<br /> testicular ',weight and degeneration of the seminiferous tubules in rats,
<br /> J guinea pigs, and rabbits were observed, Fetotoxicity in rats and ,mice
<br /> i were.observed.
<br /> I RTECS: F4totexicity, past-implantation mortality, arid extra embryonic
<br /> sz,scture; in rats and mice were oaserved. Pre-implantation mortality,
<br /> II death, and other fetal effects in mice were observed. 1
<br /> SECTION Y. CHRONIC TOXICITY
<br /> Appetite toss, reigns oss, fatigue, muscle ',weakness, headaches,
<br /> J dizziness, nervousness, irritability, anemia, irreversible blood changes,
<br /> and damage to the heart and liver. {
<br /> SECTION VI. PHYSICAL U;TA
<br /> `"oecul ar wei nt: 79.1
<br /> dol in ; Hint (at 760 mm Ho): 8O°C (376°r)
<br /> j Me!t,na aMric ;at o mm ia1: ':. 5.5°C !a2°F)
<br /> Vapor ressure (mm Fla) tat 0'C (69°,=)]: 74.0
<br />,4 ?apor ens
<br /> t Snecir'ic hravjtZ water�i): J.979
<br /> ati0an ataitea Jomercent V 10
<br /> 0
<br /> Moor
<br /> uty acetate =1): l i
<br /> k ! Z`oiuoillty in Water:, o uoT e �
<br /> Sri Fvent Jo not Lt: ,Miscible with alcohol , chloroforrm, ether, carbon
<br /> r r 7a4r_ti_ae,_caroon_cetrachloride;�lacial--acetic-acid--acetone -oils
<br /> p_
<br /> Anarance. and Odor: Clear,
<br /> colorless, flammable liquid +rith' an odor - -
<br />{ 4,sPl-res
<br /> no Fa,or ppm,
<br /> 5 (i
<br /> }Y
<br /> EMVfROOCfaC BATA
<br /> ft
<br /> Q�IS, -
<br /> E
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