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Hazard Quotient = Daily Intake <br /> RfD <br /> E = C <br /> D <br /> The hazard quotient is calculated by dividing the daily intake by the reference dose. The <br /> daily intake (Column C) is obtained by multiplying the chemical concentration in media <br /> (Column A) with the intake factor (Column B). The hazard quotient (Column E) is <br /> then derived: by dividing the daily intake (Column C) with the reference dose <br /> (Column D). <br /> The individual chemical hazard quotients are summed over all the chemicals evaluated <br /> to provide a hazard index. The total hazard index for a given receptor population is <br /> obtained by combining the hazard indices for each exposure pathway contributing to the <br /> exposure of that population. The total hazard index for' multiple pathways is calculated "T <br /> as follows: <br /> r <br /> Total!Exposure Hazard Index = Hazard Index (exposure pathway,) + Hazard <br /> Index (exposure pathwayZ) + . . .Hazard Index (exposure pathway;). <br /> Hazard indexes of noncarcinogenic risks for each receptor and pathway are summarized <br /> in Section 6.3. 4 <br /> The quantification of carcinogenic and noncaicinogenic health risks is made using a <br /> similar spread sheet calculation format. The parameters presented below represent the <br /> format utilized in the spread sheet risk calculations for carcinogenic health risks. The <br /> carcinogenic risk is calculated as follows: <br /> Lifetime <br /> Chemical Intake Daily Slope <br /> Concentration Factor Intake Factor Cancer <br /> (mg/ke) (ke/kg/day) (mg/kg/day) (mg/kg,/day)"' Risk <br /> A B C D E <br /> S:\LDC\YELLO.RPT May 4,1995 6-5 <br />