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No.354 Methyl Alcohol 11/91 _
<br /> Section 6. Health Hazard .Data -
<br /> Carcinogenicity:In 1990 repom.the IARC.NTP,and OSHA do not list methyl alcohol as a carcinogen.
<br /> Summary or Risks:Methyl alcohol is toxic mainly to the nervous system,particularly optic nerves,where damage can progress to permanent
<br /> blindness.Poisoning may also result in metabolic acidosis.Methyl alcohol oxidizes in the body to form formaldehyde and formic acid.These
<br /> derivatives are believed responsible for many of methyl alcohol's poisonous and toxic effects.Since it is eliminated slowly from the body,methyl
<br /> alcohol is considered s cumulative poison.The fatal ingestion dose is 100 to 250 ml,although death is reported from less than 33 ml.
<br /> Medical Conditions Aggravated by Umg-Term Exposure:None reported
<br /> Target Organs:Eves,central nervous system,skirt.and digestive tract. -
<br /> Primary Entry Routes:Inhalation,ingestion.sarin absorption. t
<br /> Acute effects:Inhalation can cause irritation of eyes and nose,headache`fatigue nausea,visual impairment(optic nerve neuropathy or visual
<br /> field changes)or complete and possibly permanent blindness.acidosis.convulsions,circulatory collapse,respiratory failure,and death.ingestion
<br /> can cause gastrointestinal(GI)irritation followed by the symptoms described for inhalation and possible kidney impairment.Skin contact results
<br /> in a feeling of coldness,dryness,and cracking possibly leading to dermatitis.Methyl alcohol can absorb through skin and may cause headache,
<br /> fatigue,and visual disturbances.Eye contact causes irritation and watering of eyes,inflamed Gds,and painful sensitization to light,
<br /> Chronic Effects:Chronic inhalation or skin absorption may produce visual impairment or complete blindness.
<br /> FIR ST AID
<br /> Eyes:.Gcntly lift the eyelids and flush immediately and continuously with flooding amounts of water until transponed to an emergency medical
<br /> facility.Do not lei victim rub or keep eyes tightly shut.Consult a physician immediately. '
<br /> Skin:Quickly remove contaminated clothing.Since methyl alcohol is volatile and flammable,carefully dispose of contaminated clothing.Rinse
<br /> with flooding amounts of water for at least 15 min.For reddened or blistered skin,consult a physician.Wash affected area with soap and water.
<br /> inhalation:Remove exposed person to fresh air and support breathing as needed.
<br /> Ingestion:Never give anything by mouth to an unconscious or convulsing person.if ingested,have that conscious and alert person drink 1 to 2
<br /> glasses of water,then induce vomiting.
<br /> Arter first aid,get appropriate In-plant,paramedic,or community medical support,
<br /> Dote to Physicians:Consider administering 10%ethanol in D5W intravenously to maintain ethyl alcohol blood level at 100 mg/dI.Check formic acid
<br /> in urine and measure blood pH and plasma bicarbonate.After ingestion,there is typically an 18-to 48-hr latency period before clinical toxicity
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<br /> Section 7 .Spill;Leak;::and�Disposal Troaedures :: .. `
<br /> Spil ak.Notify safety personnel,isolate area,deny entry,and stay upwind Shut o all ignition sources--noflares,smoking,or flames in
<br /> hazard area.Cleanup personnel should wear fully encapsulating,vapor-protective clothing for spills or leaks with no fare.Water spray may reduce
<br /> vapor,but not prevent 1grution in closed spaces.For small spills,use nonsparking tools to take up with earth'sand'vermicuhte,or other absorbent.
<br /> noncombustible material and place in suitable containers for later disposal.For large spills,dike far ahead of spill and await disposal.Follow
<br /> applicable OSHA regulations(29 CFR 1910.120).
<br /> Environmental Aegradation:Aquatic toxicity rating:TLm 96,over 1000 ppm.
<br /> Disposal:Contact your supplier or a licensed contractor for detailed recommendations.Follow applicable Federal.state,and local regulations.
<br /> EPA Designations OSHA Designations
<br /> Listed as a RCRA Hazardous Waste(40 CFR 26133):Hazardous Listed as an Air Contaminant(29 CFR 1910.1000,Table Z-1-A)
<br /> Waste No.U 15,
<br /> CERCLA Hazardous Substance(40 CFR 3024):Not listed.
<br /> SARA Extremely Hazardous Substance(40 CFR 355):Not listed a
<br /> SARA Toxic Chemical(40 CFR 372.65):Not listed `f
<br /> Section $ ' Special'Protectlon'Data
<br /> Goggles:Wear protective eyeglasses or chemical safety goggles,per OSHA eye-and face-protection regulations(29 CFR 1910 133).Since '
<br /> contact lens use in industry is controversial,establish your own policy.
<br /> Respirator:Seel:professional advice prior w respirator selection and use.Follow OSHA respirator regulations(29 CFR 1910.134)and,if r
<br /> necessary,wear a NIOSH-approved respirator.Select the respirator based on its suitability to provide adequate worker protection for the given
<br /> working conditions,level of airborne contamination,and presence of sufficient oxygen.For emergency or nonroutine operations(cleaiun9 spills,
<br /> reactor vessels,or storage tanks),wear an SOBA.Warning!Air-purifying respirators do nor protect.workers in oxygen-def tient atmospheres.
<br /> Other:Wear impervious gloves,boots,aprons,and gatmilets to prevent all skin contact t
<br /> Ventilation:Provide general and local explosion-proof exhaust ventilation systems to maincentrations below the OSHA
<br /> ntain airborne co �PELs
<br /> (Sec.2).Local exhaust ventilation is preferred since it prevents oantaminant disperaiom into the work area by controlling it at its source.
<br /> Safety Stations:Make available in the work area emergency eyewash stations,safety/quick.drernch showers,and washing facilities.
<br /> Contaminated}Equipment:Separate contaminated work clothes from street clothes.Launder contaminated work clothing before wearing.
<br /> Remove this material from your shoes and clean personal protective equipment-
<br /> Comments:Never eat,drink or smoke in work ureas.Practice good personal hygiene after using this material,especially before eating,drinking,
<br /> smoking,using the toilet,or applying cosmetics.
<br /> Section.9..�Special'Precautions and`Comrnents
<br /> Storage Requirements:Avoid physical damage to containers.Store.in, cool,dry,well-ventilated Ilammatiles storage arca,away from strong
<br /> oxidizers and other incompatibles.To prevent static sparks.electrically ground all equipment used in methyl alcohol storage,manufacture,and
<br /> transportation.Use nonsparking tools.
<br /> Engineering Controls:To reduce potential health hazards,use sufficient dilution or local exhaust ventilation to control hazardous airborne
<br /> contaminants and to maintain concentrations at the lowest practical level.
<br /> ns of exposed workers emphasizing neurological.kidney,liver,and
<br /> Other Precautions:Consider prepincemeat and periodic medical examinatio
<br /> visual function.Practice good personal hygiene erad housekeeping procedures.If respirators are used,institute a respiratory protection program
<br /> that includes regular training,maintenance,inspection,and evaluation.
<br /> Transportation Data(49 CFR 172.101,302)
<br /> DOT Shipping Name:Methyl alcohol rMO Shipping Name:Methanol
<br /> DOT hazard Class: Flammable liquid IMO Hazard Class:3.2
<br /> ID No.: UN1230 1D No:UN1730
<br /> DOT Label: Fiammabie liquid IMO Label.Flammable Li d.Poison
<br /> DOT Packaging Exceptions: 173.118 rMDG Packaging Group:I1 -
<br /> DOT Packaging Requirements: 173.119
<br /> AfSDS Cotteeeiva References:26.3S,73,89,100,101,103,124,126,127,132,133,136,140,143,146, 14S, 149,153,159. 163
<br /> Prepared bp:M Gannon,BA:Industrial Hygiene Review:DJ Wilson.CIH:}}Medical Review:AC Dadingwn MD,MPH;Edited by:IR Stuart�MS ��
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