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AR EMA SAFETY DATA SHEET <br /> RILSAN® 820 BLACK MAC ES <br /> 11.TOXICOLOGICAL INFORMATION <br /> Data on this material and/or its components are summarized below. <br /> Data for Undecanoic acid, 11 amino-, homopolymer(25587-80-8) <br /> Acute toxicity <br /> Oral: <br /> No deaths occurred. (Rat)LDO>2,000 mg/kg. <br /> Dermal: <br /> No deaths occurred. (Rat)LDO >2,000 mg/kg. <br /> Skin Irritation: <br /> Not irritating.(In vitro) <br /> Eye Irritation: <br /> Not corrosive(Bovine cornea) <br /> Skin Sensitization: <br /> Not a sensitizer. LLNA: Local Lymph Node Assay. (Mouse) No effect is reported. <br /> Repeated dose toxicity <br /> Subchronic dietary administration to rat, dog/No adverse systemic effects reported. <br /> Genotoxicity <br /> Assessment in Vitro: <br /> No genetic changes were observed in laboratory tests using: bacteria <br /> Other information <br /> The information presented is from representative materials with this Chemical Abstract Service(CAS)Registry <br /> number.The results vary depending on the size and composition of the test substance. <br /> Data for Kaolin,calcined (92704-41-1) <br /> Acute toxicity <br /> Oral: <br /> No deaths occurred.(Rat)LDO>2,000 mg/kg. <br /> Dermal: <br /> No deaths occurred.(Rat)LDO >5,000 mg/kg. <br /> Inhalation: <br /> No deaths occurred.(Rat)4 h LCO>2.07 mg/l. (dust) <br /> Skin Irritation: <br /> Not irritating.(Rabbit)Irritation Index:0/8. (4 h) <br /> Product code:A09106 Version 2.0 Issued on: 04/11/2015 Page: S/12 <br /> quick-FDS(1726&63015-00974010659]-2015-04-11-23:03:36 <br />