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Instability Temperature: Not available. <br />Conditions of Instability: Incompatible materials <br />Incompatibility with various substances: Reactive with oxidizing agents, reducing agents. <br />Corrosivity: Non -corrosive in presence of glass. <br />Special Remarks on Reactivity: <br />Superficially oxidized on exposure to air. Reacts with aqueous solutions of sodium or potassium bicarbonate. Reacts with <br />dilute mineral acids with evolution of hydrogen and formation of divalent manganous salts. Reacts with fluorine and chlorine to <br />produce di or tri fluoride, and di and tri chloride, respectively. In the form of powder, it reduces most metallic oxides on heating. <br />On heating, it reacts directly with carbon, phosphorus, antimony, or arsenic. Also incompatible with hydroxides, cyanides, <br />carbonates. <br />Special Remarks on Corrosivity: Not available. <br />Polymerization: Will not occur. <br />Routes of Entry: Inhalation. Ingestion. <br />Toxicity to Animals: Acute oral toxicity (LD50): 9000 mg/kg [Rat]. <br />Chronic Effects on Humans: May cause damage to the following organs: blood, lungs, brain, central nervous system (CNS). <br />Other Toxic Effects on Humans: <br />Hazardous in case of inhalation. Slightly hazardous in case of skin contact (irritant), of ingestion. <br />Special Remarks on Toxicity to Animals: Not available. <br />Special Remarks on Chronic Effects on Humans: <br />Manganese can cross the placenta. May cause cancer (tumorigenic) based on animal data. <br />Special Remarks on other Toxic Effects on Humans: <br />Acute Potential Health Effects: Skin: May cause skin irritaiton Eyes: Dust may cause mechanical irritation. Inhalation: Dust <br />may cause respiratory tract irritation. May cause "Metal Fume Fever" which may include flu-like symptoms (fever, chills, <br />upset stomach, vomiting, weakness, headache, body aches, muscle pains, dry mouth and throat, coughing, tightness of <br />the chest). May affect behavior/Central Nervous system (change in motor activity, torpor, nervousness, tremor, yawning, <br />mood swings, irritability, restlessness, fatigue, headache, apathy, languor, insomnia than somnolence, hallucinations, <br />delusions, uncontrollable laughter followed by crying, compulsions, aggressivness, weakness in legs, memory loss, decreased <br />libido, impotence, salivation, hearing loss, slow gait, ), and respiration (dyspnea, shallow respiration, cyanosis, alveolar <br />inflammation). Ingestion: Repeated or prolonged exposure from ingestion may affect brain (degenerative changes), blood <br />and metabolism. Ingestion: May cause digestive tract irritation. There is a low gastrointesitnal absorption of manganese. <br />Chronic Potential Health Effects: Inhalation: Repeated or prolonged exposure from inhalation may affect brain (degeneratiave <br />changes), behavior/Central Nervous system with symptoms to acute exposure. May also affect liver (chronic liver disease, <br />jaundice) Ingestion: Repeated or prolonged exposure from ingestion may affect brain, blood and metabolism <br />Section 12: Ecological' Information <br />Ecotoxicity: Not available. <br />BOD5 and COD: Not available. <br />Products of Biodegradation: <br />Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise. <br />Toxicity of the Products of Biodegradation: The product itself and its products of degradation are not toxic. <br />Special Remarks on the Products of Biodegradation: Not available. <br />p. 4 <br />