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2518 E Boeing Way, Stockton Record ID PR0538472 <br /> 4/18/2019 <br /> Photo 12: Light Blue in 481 GAL-80355 SDS page 4. <br /> /th <br /> 13 <br /> In lifetime inhalation studies Of rats,airborne respirable size titanium p <br /> dioxide pani pati <br /> chronic 7vxicity: <br /> been shown to cause lung tumors at concentrations associated with substantial Q 4 <br /> burdens and consequential pm91ars did not develop lung umors under onary overload and inflammation. os milar le r 6 r`T � <br /> animals ouch as mice and ha sti " �• , .$ <br /> titanium dioxide. Human epidemfology studies do not suggest an association between <br /> occupallonaf exposure to titanium dioxide and risk for cancer.Contains crystalline silica <br /> causes silicosis and lung cancer. • <br /> carcinogenic Effects: Respirable crystalline silicaogee has been and is <br /> as a Group I(sufficient evidence Which <br /> in humar:s <br /> carcinogenicity)carcinogenic by be <br /> and is listed by NTP as a substance which may F' <br /> reasonably he anticipated to be a carcinogen. Crystalline silica is also a knG"cause of � � `�3 <br /> sillcosis,a non-cancerous lung disease caused by excessive exposure to crystalline silica. ¢p r <br /> IARC has identified Cobalt and Cobalt compounds as"possibly carcinogeniC"as a group.The <br /> International Agency for Research on Cancer(IARC)has determined alcoholic beverage.are r <br /> carcinogenic to humans(Group 1)and the occurrence of malignant tumors of the oral cavity, 44r p,'r <br /> pharynx,farynx,esophagus and liver is causally related to the consumption of alcoholic rysq,� <br /> beverages In humans.Animal studies on ethanol do not provide sufficient Indicadon of <br /> carcinagen}city. <br /> Components NIOSH-Pocket Guide-Target Organs <br /> Ethanal ayes respiratory system CNS liver skin blood reproductive system ... <br /> Titanium Dioxide Respiratory system. 1� <br /> Quartz 5111Ca eyes respiratory system -:'J <br /> Chromium eyes respiratory system skin <br /> Component Information,If any,Is listed below <br /> Frit <br /> LDS0s and LC50s: Oral LD50{Rat)=2000 mglkg <br /> NTP: ' Known Human Carcinogen <br /> NIPS.Carcinogen: Reasonably Anticipated To Be A Human Carcinogen <br /> IARC-Group 1: Listed <br /> IARC-Group RA: Listed <br /> IARC-Group 28: Listed <br /> 2-Eth Ihexonol <br /> Lli and LC50a: Oral LD50(flat)=1515-2774 mglkg <br /> Ethanol <br /> LD50s and!.Cage: Inhalation LC50(Rat)=124.7 mgll- <br /> Oral LD50(Rat)=7000 mglkq <br /> OSHA•Select Carcinogens: Present <br /> !YTP: Known Human Carcinogen <br /> IARC-Group 1: Listed <br /> Tltenlum Dioxide <br /> LD50s and LC50s: Oral 1_050(Rat).10000 mglkg <br /> OSHA•Select Carcinogens: Present <br /> IARC•Group 28: Listed <br /> Quarts silica <br /> 1-050s and LC50a: Oral LD50(Rat)=500 mglkg <br /> OSHA-Si Carcinogens: Present <br /> NTP: Known Human Carcinogen <br /> IARC-Group 1: Listed - <br /> Cobalt chromite bitU rNn a Incl 3•;i <br /> IARC-Group 28: Listed <br /> t <br /> Pro-rtpn+e-—40M L <br /> tght otos to M1 <br /> 1§rgi4 ei?:;: <br /> G. <br /> John Alaniz, REHS Page 12 of 20 <br />