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12 / 20 / 2005 15 : 58 . FAX U003 <br /> 12 / 20 / 2005 15220 4444444444444444444 IKG VISCO : PAGE 06 lilt <br /> Iron ( Fe ) <br /> Subjecting iron and alloys containing iron to high temperatures . ( such a ; <br /> during welding ) will cause the formation of iron oxide . Long term <br /> exposure to iron oxide fumes or dusts has been associated with beenig �. <br /> lung condition known as siderosis which is observable as an x- ray, <br /> changes No physical impairment of lung function has been linked to <br /> siderosis . <br /> i IIS <br /> Manganese ( Mn ) the oxide or salts of Mn . , elementWU" ' 3 <br /> a Vg +EO , <br /> A �A k- -� a ®�n s u <br /> Mn . exhibits very low toxicity . The dusts and fumes can ac as minor <br /> irritants: to the eyes and respiratory tract . Both acute and chron3� <br /> exposures may adversely affect the central nervous system ( CNS ) , bi{t <br /> symptoms are more likely to occur after at leasi I o weak ase , <br /> ars <br /> prolonged or repeated exposures . Early symptoms y <br /> the lower extrazities , sleepiness , salivation , nervousness , and apath ' <br /> In more advanced stages , severe muscular incoordination , . impair4 <br /> speech , spastic walking , mask- like facial expressions and uncontrollable <br /> laughter may occur . Manganese fumes have also been reported to result h <br /> metal fume fever , a flulike syndrome with symptoms such as dizziness <br /> chills , fever , headache and nausea . An increased incidence of pneumoniAll, <br /> bronchitis and pneumonitis has been reported in some worker populatio#6 <br /> exposed to manganese . Animal studies indicate that manganese exposure <br /> may increase susceptibility to bacterial and viral infections . <br /> Chromium ( Cr ) chromium are heavily dependent ups ' <br /> The toxicity and health hazards of <br /> its oxidation state . The elemental ( as in the metal ) divalent a ',d <br /> trivalent for'ins are very low toxicity . The hexavalent form ( such 08 <br /> occurs in chromates and chromic aoid ) is very toxic and can produce: bo h <br /> acute and chronic effects . Adverse effects on the skin May inclule <br /> ulcerations , irritative dermatitis , and allergic skin reactions . AdverOa <br /> effects on the respiratory system may include bronchospasms , edem' , <br /> hypersecretion , bronchitis , irritation , allergic asthmatic reaction , <br /> and ulceration and perforation of the nasal septum . Respiratory symptons <br /> may include coughing and wheezing , shortness of breath , and nasal itc . <br /> Eye irritation or inflammation can also be produced . Exposure to 00 0 <br /> hexavalent chromium compounds have also been shown to be associated wikh <br /> increased rink of lung cancer . <br /> Nickel. ( Ni ) <br /> Ni fumes and dusts are respiratory irritants and may cause a seve;'�° e <br /> pneumonitis . skin contact with nickel and its compounds may causeej $n <br /> allergic dermatitis . The resulting skin rash is often referred to ► as <br /> 11nickel itch " . Nickel and its compounds may also produce eye irritatidfi , <br /> particularly on the inner surfaces of the eyelids ( i . e . conjunctinv ) a <br /> Animal and/ or apidecesedgincidcvlinked <br /> nickel and <br /> certain ni <br /> 41 <br /> compounds to an increased incidence of cancer ofthe lug and nakl <br /> passages . <br /> � II <br /> . i <br /> p <br /> i <br />