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FEB 13 '97 11:44AN DOW CHI M PEP TET M A 1 L n 1 " L a M a D A T A S H E E T P,3114: 2 Product : TRICHLOROETHYLENE INDUSTRIAL GRADE Product Code: 87444 Effective Date: 02/07/96 Date Printed: 02/13/97 MSD: 000168 ---------------------------- -------------------------------------------- 3 . HAZARDS IDENTIFICATION (CONTINUED) larger than that may cause serious injury, even death. If aspirated (liquid enters the lung) , may be rapidly absorbed through the lungs and result in injury to other body systems . KMALATION; In confined or poorly ventilated areas, vapors can readily accumulate and can cause unconsciousness and death. Excessive exposure may cause irritation to upper respiratory tract . Excessive exposure may increase sensitivity to epine- phrine and increase myocardial irritability (irregular heart- beats) . May cause alcohol intolerance often manifested by temporary reddening of the skin called 'degreaser' s flush' . Minimal anesthetic or irritant effects may be seen around 200-400 ppm trichloroethylene. Levels in the range of 1000-2000 ppm may rapidly cause dizziness and drunkenness . Progressively nigher levels or longer exposure may cause unconsciousness and death and may be immediately hazardous to life. SYSTEMIC (OTHER TARGET ORGW) EFFECTS: Alcohol consumed before or after exposure may increase adverse effects . Trichloroethylene is reported to have caused hearing loss in laboratory animals upon repeated exposure to 2500 ppm or higher (orders of magnitude greater than the PEL) ; however, the relevance of this to humans is unknown. Repeated exposure may cause central or possibly even peripheral nervous system effects; high levels have caused liver or kidney effects in laboratory animals . CANCER INFORMATION: A positive carcinogenic response has occurred only in mice given large doses of trichloroethylene. Data suggest a nonmutagenic mechanism for tumor formation implying that nontoxic doses of trichloroethylene should pose little or no carcinogenic hazard for man. Butylene oxide has been shown to produce benign and malignant tumors in rats but not mice . These tumors occurred only following high exposure levels which first produced chronic upper respiratory tract irritation. Butylene oxide is not believed to pose a carcinogenic risk to man when handled as recommended, This mixture contains a component (s) which. are listed as potential carcinogens for hazard communication_ purposes under OSHA Standard 29 CFR 1910 . 1200 . Components listed by IARC: trichloroethylene. TERATOLOGY (BIRTH DEFECTS) : Birth defects are unlikely. (Continued on Page 3 ) (R) Indicates a Trademark of The Dow Chemical Company