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Management of RCRA/Hazardous Pharmaceutical Waste Page 2 of. 7 <br /> Conservation and Recovery Act (RCRA) , including chemotherapy/biotherapy wastes are stored, <br /> handled, packaged, transported and disposed of in accordance with all federal, state and local <br /> government regulations . <br /> III . Definitions : <br /> Hazardous Drugs (HD ) - Drugs that are capable of causing toxicity to personnel and others who come <br /> in contact with them . Hazardous drugs pose a potential health risk to personnel who prepare, handle, <br /> administer and dispose of these drugs . Drugs may be classified as hazardous when they possess any <br /> one of the following characteristics : <br /> - Genotoxicfty <br /> - Carcinogenicity <br /> - Teratogenicity <br /> Reproductive toxicity <br /> - Organ toxicity at low doses <br /> Structure and toxicity profiles of new drugs mimic existing drugs determined to be hazardous by the <br /> above criteria <br /> Potential exposure routes to hazardous drugs may occur through inhalation , skin contact, skin <br /> absorption, ingestion or injection . <br /> P - listed waste - includes unused, commercial chemical products that are acutely hazardous waste when <br /> discarded. The P -list can be found in Federal regulations . <br /> U- listed waste - includes unused, commercial chemical products that are hazardous waste when <br /> discarded . The U-list can be found in Federal regulations . <br /> Ignitability characteristic - identifies hazardous wastes that can create fires under certain conditions, <br /> are spontaneously combustible, or have a flash point of less than 60 ° C ( 140 °F) . <br /> Corrosivity characteristic - identifies wastes that are acids or bases (aqueous solutions with pH less <br /> than or equal to 2 , or greater than or equal to 12 . 5 ) or liquids that are capable of corroding metal <br /> containers . <br /> Reactivity characteristic - identifies wastes that readily explode or undergo violent reactions or <br /> release toxic gases or fumes when heated, compressed, or mixed with water <br /> Toxicity characteristic - identifies wastes likely to leach dangerous concentrations of toxic chemicals <br /> into ground water. <br /> D -listed wastes — identifies wastes possessing one or more characteristics of Ignitability , Corrosivity , <br /> Reactivity, or Toxicity <br /> IV . Text : <br /> Regulatory bodies that oversee pharmaceutical waste management are : <br /> A . Environmental Protection Agency (EPA) <br /> B . Oeaartment of Transporta_ion (TOOT) <br /> C . Drug Enforcement Agency (DEA) <br /> D . Occupational Safety and Health Administration ( OSHA) <br /> E . California Department of Public Health ( CDPH) <br /> F . California State .Pharmacy Board <br /> G . Local Publicly Owned Treatment Works (POTW) <br /> httr) : HdhaltsOl /nolicv/policy . nsf/2bOl45f9n l 8Obc28725727600642564/ 1 a68480abe9cecfl . . . 3 / 18 /2015 <br />